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PE/Cyanine7 anti-human CD326 (EpCAM) Antibody
产品名称:
PE/Cyanine7 anti-human CD326 (EpCAM) Antibody
产品类别:
抗体
产品编号:
369815
产品应用:
369815
[价格]
规格 价格 库存
25tests ¥ 2112 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC -?Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Additional Product Notes
BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
Application References

(PubMed link indicates BioLegend citation)
  1. Strnad J, et al. 1989. Cancer Res. 49:314.
  2. Munz M, et al. 2004. Oncogene 23:5748.
  3. Rao CG, et al. 2005. Int. J. Oncol. 27:49.
Product Citations
  1. Sontheimer-Phelps A, et al. 2019. Cell Mol Gastroenterol Hepatol. 9:507. PubMed
RRID
AB_2650911 (BioLegend Cat. No. 369815) AB_2650912 (BioLegend Cat. No. 369816)

Antigen Details

Structure
Type I transmembrane protein, contains six disulfide bridges, one THYRO domain, approximate molecular weight 40 kD.
Distribution

Highly expressed in bone marrow, colon, lung, and most normal epithelial cells. Also highly expressed on carcinomas of gastrointestinal origin. Expressed during early erythrogenesis.

Function
Homotypic calcium-independent cell adhesion. CD326 is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation.
Cell Type
Epithelial cells
Biology Area
Cancer Biomarkers, Cell Biology, Cell Proliferation and Viability, Immunology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1.?Strnad J, et al. 1989. Cancer Res. 49:314.
2. Munz M, et al. 2004. Oncogene 23:5748.
3. Rao CG, et al. 2005. Int. J. Oncol. 27:49.?

Gene ID
4072 View all products for this Gene ID
UniProt
View information about CD326 on UniProt.org

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