APC anti-human CD326 (EpCAM) Antibody
- 产品名称：
- APC anti-human CD326 (EpCAM) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 369809
- 产品应用：
- 369809
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1788 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC -?Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Strnad J, et al. 1989. Cancer Res. 49:314.
- Munz M, et al. 2004. Oncogene 23:5748.
- Rao CG, et al. 2005. Int. J. Oncol. 27:49.
- Product Citations
-
- Zhou Y, et al. 2020. Cancer Cell. 38(6):818-828.e5. PubMed
- Fan X, et al. 2021. Genome Biol. 22:195. PubMed
- Rush CM, et al. 2022. Sci Rep. 12:19731. PubMed
- RRID
- AB_2650906 (BioLegend Cat. No. 369809) AB_2650907 (BioLegend Cat. No. 369810)
- Structure
- Type I transmembrane protein, contains six disulfide bridges, one THYRO domain, approximate molecular weight 40 kD.
- Distribution
-
Highly expressed in bone marrow, colon, lung, and most normal epithelial cells. Also highly expressed on carcinomas of gastrointestinal origin. Expressed during early erythrogenesis.
- Function
- Homotypic calcium-independent cell adhesion. CD326 is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation.
- Cell Type
- Epithelial cells
- Biology Area
- Cancer Biomarkers, Cell Biology, Cell Proliferation and Viability, Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1.?Strnad J, et al. 1989. Cancer Res. 49:314.
2. Munz M, et al. 2004. Oncogene 23:5748.
3. Rao CG, et al. 2005. Int. J. Oncol. 27:49.?
- Gene ID
- 4072 View all products for this Gene ID
- UniProt
- View information about CD326 on UniProt.org
