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APC anti-human CD43 Antibody
产品名称：
APC anti-human CD43 Antibody
产品类别：
抗体
产品编号：
343205
产品应用：
343205
[价格]
规格 价格 库存
25tests ￥ 1224 1

产品详情

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Cynomolgus
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
MV4-11 cell line
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Red Laser (633 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Rosenkranz AR, et al. 1993. Immunology. 80:431
  2. Skubitz KM, et al. 1998. J. Leukoc. Biol. 64:800
Product Citations
  1. Abud EM et al. 2017. Neuron. 94(2):278-293 . PubMed
  2. Grubman A, et al. 2020. Stem Cell Reports. 1.290277778. PubMed
  3. Guney-Esken G, et al. 2021. Stem Cell Res Ther. 12:287. PubMed
  4. Ng E, et al. 2016. Nat Biotechnol. 34:1168-1179. PubMed
  5. Rai MA, et al. 2020. Retrovirology. 17:35. PubMed
  6. Bruveris FF, et al. 2020. Development. 147:00:00. PubMed
  7. Guney-Esken G, et al. 2021. Methods Mol Biol. 2549:23. PubMed
RRID
AB_2194073 (BioLegend Cat. No. 343205) AB_2194072 (BioLegend Cat. No. 343206)

Antigen Details

Structure
Single chain, type I transmembrane glycoprotein with abundant O-glycosylation and sialylation sites, 95-130 kD.
Distribution

Most hematopoietic cells, including peripheral T cells, NK cells, granulocytes, monocytes, thymocytes, platelets, plasma cells, activated B cells, and hemotopoietic progenitor cells.

Function
Plays dual roles in cell-cell adhesion and anti-adhesion, costimulation of cell activation and survival, inducing apoptosis of T cells and hematopoietic progenitors.
Ligand/Receptor
CD54, Siglec-1
Biology Area
Immunology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Neil Barclay A, et al. 1997. The Leucocyte Antigen Facts Book:Second Edition. Page 238
2. Killeen A, et al. 1987. EMBO J. 6:4029.
3. Thurman EC, et al. 1998. Intl. Immunol. 10:691.
4. Onami TM, et al. 2002. J. Immunol. 168:6022.
5. Tong J, et al. 2004. J. Exp. Med. 199:1277.
6. Jones AT, et al. 1994. J. Immunol. 153:3426.

Gene ID
6693 View all products for this Gene ID
UniProt
View information about CD43 on UniProt.org

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