Purified anti-human CD18 Antibody
- 产品名称:
- Purified anti-human CD18 Antibody
- 产品类别:
- 抗体
- 产品编号:
- 366302
- 产品应用:
- 366302
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Purified human LFA-1
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats of this clone) include: activation of LFA-1 and MAC-11,2. The LEAF? or Ultra-LEAF? purified antibody (Endotoxin < EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for function assays (contact our custom solutions team).
- Application References
(PubMed link indicates BioLegend citation) -
- Petruzzelli L, et al. 1995. J. Immunol. 155:854. (Activ)
- Lu C, et al. 2001. J. Immunol. 166:5629. (Activ)
- Product Citations
-
- Blandine Monel et al. 2019. Cell reports. 27(1):142-153 . PubMed
- RRID
- AB_2565276 (BioLegend Cat. No. 366302)
- Structure
- 90 - 95 kD type I transmembrane glycoprotein.
- Distribution
-
Leukocytes.
- Function
- Cell adhesion and signaling.
- Interaction
- Integrin, type I transmembrane glycoprotein, associates with CD11a, CD11b, or CD11c
- Ligand/Receptor
- ICAMs.
- Cell Type
- Leukocytes
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Anderson DC, et al. 1987. Annu. Rev. Med. 38:175.
2. Springer TA. 1994. Cell 76:301.
- Gene ID
- 3689 View all products for this Gene ID
- UniProt
- View information about CD18 on UniProt.org