PE anti-mouse CD282 (TLR2) Antibody
- 产品名称：
- PE anti-mouse CD282 (TLR2) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 148603
- 产品应用：
- 148603
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse TLR2-transfected Ba/F3 cells.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
1. Shibata T, et al. 2012. Int. Immunol. 24:613. (FC)
- Product Citations
-
- Michela Miani et al. 2018. Cell metabolism. 28(4):557-572 . PubMed
- Takayanagi Y, et al. 2020. J Clin Med. 9:00. PubMed
- Jeljeli M, et al. 2020. Cell Rep. 33:108325. PubMed
- Lax N, et al. 2020. J Neuroinflammation. 17:55. PubMed
- Di Lorenzo A, et al. 2022. Oncoimmunology. 11:2086752. PubMed
- Lee GR, et al. 2021. JCI Insight. 6:. PubMed
- RRID
- AB_2564119 (BioLegend Cat. No. 148603) AB_2564120 (BioLegend Cat. No. 148604)
- Structure
- 89 kD type I transmembrane protein with 14 leucine-rich repeats (LRR) on its extracellular region and one toll/IL-1R (TIR) domain on its intracellular region.
- Distribution
-
Monocytes, macrophages, dendritic cells, granulocytes, endothelial cells, epithelial cells.
- Function
- Activates innate host defense against a diverse set of pathogens.
- Interaction
- TLR1, TLR6.
- Ligand/Receptor
- Microbial lipoproteins, peptidoglycans, lipoteichoic acid.
- Cell Type
- Dendritic cells, Endothelial cells, Epithelial cells, Granulocytes, Macrophages, Monocytes
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Signal Transduction
- Molecular Family
- CD Molecules, Toll Like Receptors
- Antigen References
-
1. Du B, et al. 2013. J. Biol. Chem. 288:15131.
2. Zivkovic A, et al. 2011. J. Immunol. 186:1608.?
3. Okun E, et al. 2010. J. Neurochem. 114:462.?
4. Kim S, et al. 2009. Nature. 457:102.
- Gene ID
- 24088 View all products for this Gene ID
- UniProt
- View information about CD282 on UniProt.org
