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PE anti-mouse CD223 (LAG-3) Antibody
产品名称:
PE anti-mouse CD223 (LAG-3) Antibody
产品类别:
抗体
产品编号:
125207
产品应用:
125207
[价格]
规格 价格 库存
25µg ¥ 1056 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Murine CD223-Ig fusion protein
Formulation
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Workman CJ, et al. 2002. Eur. Immunol. 32:2255. (IP, ELISA)
  2. Workman CJ, et al. 2005. J. Immunol. 174:688. (FC)
  3. Li N, et al. 2004. J. Immunol. 173:6806. (IP, ELISA)
Product Citations
  1. Bertrand F, et al. 2017. Nat Commun. 8:2256. PubMed
  2. Logan K Smith et al. 2018. Immunity. 48(2):299-312 . PubMed
  3. Dong MB, et al. 2020. Cell. 178(5):1189-1204.e23.. PubMed
  4. Clement M, et al. 2016. PLoS Pathog. 12:e1006050. PubMed
  5. Lu SX, et al. 2021. Cell. . PubMed
  6. Yu AI, et al. 2020. Cell Rep. 107471:31. PubMed
  7. Rodriguez AB, et al. 2021. Cell Reports. 36(3):109422. PubMed
  8. Mitchell JE, et al. 2021. Cell Reports. 35(2):108966. PubMed
  9. Lv Z, et al. 2020. Oncoimmunology. 9:1747688. PubMed
  10. Wagle MV, et al. 2021. Nat Commun. 12:2782. PubMed
  11. Gozgit JM, et al. 2021. Cancer Cell. :. PubMed
  12. Hu Q, et al. 2018. Nat Biomed Eng. 0.660416667. PubMed
  13. Fortner K, et al. 2017. Journal of Autoimmunity. 10.1016/j.jaut.2017.05.003. PubMed
  14. Zuo S, et al. 2021. J Immunother Cancer. 9:. PubMed
  15. Shen M, et al. 2022. Nat Cancer. 3:60. PubMed
  16. RY H, et al. 2016. Oncoimmunology. 6:e1249561. PubMed
  17. Yang BH, et al. 2020. Cell Reports. 27(12):3629-3645.e6.. PubMed
  18. Wedekind MF, et al. 2021. iScience. 24(7):102759. PubMed
  19. Alenazy MF, et al. 2022. PLoS One. 17:e0271689. PubMed
  20. De Souza ALS, et al. 2018. Neurol Ther. 7:103. PubMed
  21. Lu Y, et al. 2018. Cancer Cell. 33:1048. PubMed
  22. Katsuyama T, et al. 2021. Cell Reports. 36(1):109339. PubMed
  23. Rudd CE, et al. 2020. Cell Reports. 30(7):2075-2082. PubMed
RRID
AB_2133344 (BioLegend Cat. No. 125207) AB_2133343 (BioLegend Cat. No. 125208)

Antigen Details

Structure
Ig superfamily
Distribution

T cells and NK cells, as well as T regulatory cells

Cell Type
NK cells, T cells, Tregs
Biology Area
Immunology, Inhibitory Molecules
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Baixeras E et al. 1992. J. Exp. Med. 176:327.

Gene ID
16768 View all products for this Gene ID
UniProt
View information about CD223 on UniProt.org

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