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APC anti-mouse CD223 (LAG-3) Antibody
产品名称:
APC anti-mouse CD223 (LAG-3) Antibody
产品类别:
抗体
产品编号:
125209
产品应用:
125209
[价格]
规格 价格 库存
25µg ¥ 1128 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Murine CD223-Ig fusion protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Workman CJ, et al. 2002. Eur. Immunol. 32:2255. (IP, ELISA)
  2. Workman CJ, et al. 2005. J. Immunol. 174:688. (FC)
  3. Li N, et al. 2004. J. Immunol. 173:6806. (IP, ELISA)
Product Citations
  1. Soon MSF, et al. 2020. Nat Immunol. 1.984027778. PubMed
  2. Wu J et al. 2017. Immunity. 47(6):1114-1128 . PubMed
  3. Ferrere G, et al. 2021. JCI Insight. 6:. PubMed
  4. Piepke M, et al. 2021. J Neuroinflammation. 18:265. PubMed
  5. Choi H et al. 2019. Cell Rep. 27(3):806-819 . PubMed
  6. DeLong JH, et al. 2019. Immunohorizons. 3:13. PubMed
  7. Wu J, et al. 2020. Sci Adv. 6:eaba3458. PubMed
  8. Mitchell JE, et al. 2021. Cell Reports. 35(2):108966. PubMed
  9. Sande O, et al. 2016. J Immunol. 196: 691 - 702. PubMed
  10. Dikiy S, et al. 2021. Immunity. 54(5):931-946.e11. PubMed
  11. Ma X et al. 2019. Cell Metab. 30(1):143-156 . PubMed
  12. Wang J et al. 2018. Cell. 176(1-2):334-347 . PubMed
  13. Snell LM, et al. 2018. Immunity. 49:678. PubMed
  14. Miyakoda M, et al. 2012. J Immunol. 189:4396. PubMed
  15. , et al. 2021. Eur J Immunol. 51:2708. PubMed
  16. Chen X, et al. 2021. Cell Rep. 37:109991. PubMed
  17. Ying Zhang et al. 2017. Cancer cell. 32(3):377-391 . PubMed
  18. Moore MJ et al. 2018. eLife. 7 pii: e33057. PubMed
  19. Zhang C, et al. 2021. J Immunother Cancer. 9:. PubMed
  20. Hartmann W, et al. 2020. Cell Reports. 29(8):2243-2256.e4.. PubMed
  21. Li M, et al. 2020. J Immunother Cancer. 8:00. PubMed
RRID
AB_10639935 (BioLegend Cat. No. 125209) AB_10639727 (BioLegend Cat. No. 125210)

Antigen Details

Structure
Ig superfamily
Distribution

T cells and NK cells, as well as T regulatory cells

Cell Type
NK cells, T cells, Tregs
Biology Area
Immunology, Inhibitory Molecules
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Baixeras E et al. 1992. J. Exp. Med. 176:327.

Gene ID
16768 View all products for this Gene ID
UniProt
View information about CD223 on UniProt.org

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