Purified anti-human CD8a Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 708	1

Product Details

Verified Reactivity

Human, Mouse, Rat

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

A 13 amino acid synthetic peptide from the C-terminal cytoplasmic domain of the alpha chain of the human CD8 molecule.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C.

Application

IHC-P - Quality tested
Activ, FC, IHC-F, WB - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5.0 - 10 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats) include activation³, flow cytometry⁴, immunohistochemical staining of frozen tissue sections², and Western blotting⁵.

Application References (PubMed link indicates BioLegend citation)

McQuitty E, et al. 2014. J. Cutan. Pathol. 41:88. (IHC-P)
Petukhova L, et al. 2010. Nature 466:113. (IHC-F)
Clement M, et al. 2011. J. Immunol. 187:654. (Activ)
MarTchal R, et al. 2010. BMC Cancer 10:340. (FC)
Pontiggia L, et al. 2008. J. Invest. Dermatol. 129:480. (WB)

Product Citations

Wen J, et al. 2020. J Pathol Clin Res. 0.36875. PubMed
Giadans CG, et al. 2019. J Viral Hepat. 26:727. PubMed
Zheng Y, et al. 2022. iScience. 25:103785. PubMed
Rye IH, et al. 2022. Mol Oncol. 16:88. PubMed
Schwabenland M, et al. 2021. Immunity. . PubMed
Sade–Feldman M, et al. 2018. Cell. 175:998. PubMed
Chang MH, et al. 2021. Cell Rep. 37:109902. PubMed

RRID

AB_2650657 (BioLegend Cat. No. 372902)

Antigen Details

Structure: Ig superfamily, homodimer or heterodimer with CD8β.
Distribution: Majority of thymocytes, T cell subset, NK cells.
Function: MHC class I co-receptor, thymic differentiation, T-cell activation.
Ligand/Receptor: MHC class I molecules.
Cell Type: Thymocytes, T cells, NK cells
Biology Area: Immunology
Molecular Family: CD Molecules
Antigen References: 1.?McQuitty E,?et al.?2014.?J. Cutan. Pathol.?41:88.
Gene ID: 100387674 View all products for this Gene ID
UniProt: View information about CD8a on UniProt.org

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