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Alexa Fluor® 647 anti-human CD44 Antibody
产品名称:
Alexa Fluor® 647 anti-human CD44 Antibody
产品类别:
抗体
产品编号:
397511
产品应用:
397511
[价格]
规格 价格 库存
25tests ¥ 1212 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 647 under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC -?Quality tested
IHC-P - Verified

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?L per million cells in 100 ?L staining volume or 5 ?L per 100 ?L of whole blood.?For immunohistochemistry, a concentration range of 5.0?- 10??g/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor? 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm.


Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

View full statement regarding label licenses
Excitation Laser
Red Laser (633 nm)
RRID
AB_2860988 (BioLegend Cat. No. 397511) AB_2860989 (BioLegend Cat. No. 397512)

Antigen Details

Structure
Variable splicing of CD44 gene generates many CD44 isoforms, 80-95 kD
Distribution

All leukocytes, epithelial cells, endothelial cells, hepatocytes, mesenchymal cells

Function
Leukocyte attachment and rolling on endothelial cells, stromal cells and ECM
Interaction
Endothelial cells, Epithelial cells, Leukocytes, Mesenchymal cells, Mesenchymal Stem Cells, B cells, Tregs
Ligand/Receptor
Hyaluronan, MIP-1β, fibronectin, collagen
Cell Type
B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Biology, Immunology
Molecular Family
CD Molecules
Antigen References
  1. Barclay AN,?et al.?1997. The Leukocyte Antigen FactsBook Academic Press.
  2. Haynes BF,?et al.?1991.?Cancer Cells. 3:347.
  3. Goldstein LA,?et al.?1989.?Cell. 56:1063.
  4. Mikecz K,?et al.?1995.?Nat. Med.?1:558.
  5. Hegde V,?et al.?2008.?J. Leukocyte Biol.?84:134.
  6. Liu T,?et al.?2009.?Biol Direct. 4:40.
Gene ID
12505 View all products for this Gene ID 960 View all products for this Gene ID
UniProt
View information about CD44 on UniProt.org

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