Purified anti-human CD244 (2B4) Antibody
- 产品名称：
- Purified anti-human CD244 (2B4) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 329502
- 产品应用：
- 329502
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
WB - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats) include: inducing cytokine production by NK cells, enhancing NK cytotoxicity, and Western blotting.
- Application References
(PubMed link indicates BioLegend citation) -
- Valiante NM and Trinchieri G. 1993. J. Exp. Med. 178:1397.
- Chuang SS, et al. 2000. Immunology. 100:378.
- Hoffmann SC, et al. 2011. J. Immunol. 186:2757. PubMed
- Rossi LE, et al. 2012. J Leukoc Biol. 91:321. PubMed
- Correia DV, et al. 2011. Blood 118:992. (FC) PubMed
- Product Citations
-
- Friebel E, et al. 2020. Cell. 181(7):1626-1642.e20. PubMed
- R?lle A, et al. 2018. Cell Rep. 24:1967. PubMed
- Vivanco Gonzalez N, et al. 2022. STAR Protoc. 3:101280. PubMed
- O'Boyle KC, et al. 2020. Methods Mol Biol. 2111:1. PubMed
- Olin A, et al. 2018. Cell. 174:1277. PubMed
- Zhuang X, et al. 2019. Cancer Immunol Res. 0.94375. PubMed
- Hoffmann S, et al. 2011. J Immunol. 186:2757. PubMed
- Bengsch B et al. 2018. Immunity. 48(5):1029-1045 . PubMed
- Kim N, et al. 2020. Cancers (Basel). 12:. PubMed
- Lakshmikanth T, et al. 2020. Cell Reports. 32(3):107923. PubMed
- RRID
- AB_1279194 (BioLegend Cat. No. 329502)
- Structure
- 38 kD type I transmembrane protein, CD2 family member, Ig superfamily
- Distribution
-
NK, T subset, monocytes, basophils, and eosinophils
- Function
- Activation and inhibition of NK cell function
- Ligand/Receptor
- CD48
- Cell Type
- Basophils, Eosinophils, Monocytes, NK cells, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Lee KM, et al. 2003. J. Immunol. 170:4881.
2. Chlewicki LK, et al. 2008. J. Immunol. 180:8159.
3. Messmer B, et al. 2006. J. Immunol. 176:4646.
4. Boles KS, et al. 2001. Immunol. Rev. 181:234.
- Gene ID
- 51744 View all products for this Gene ID
- UniProt
- View information about CD244 on UniProt.org
