PE anti-human CD30 Antibody
- 产品名称：
- PE anti-human CD30 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 333906
- 产品应用：
- 333906
[价格]
| 规格 |
价格 |
库存 |
| 100tests |
￥ 3072 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human CD30 boosted with THP-1 cell line
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported application: in combination with IL-2 and PMA to induce T cell clone proliferation.
- Application References
(PubMed link indicates BioLegend citation) -
- Leca G, et al. 1994. Cell. Immunol. 156:230.
- Product Citations
-
- Lobastova L, et al. 2021. Frontiers in Cell and Developmental Biology. 9:698503. PubMed
- D?rsam B, et al. 2018. Front Immunol. 7:e34961. PubMed
- RRID
- AB_2207595 (BioLegend Cat. No. 333906)
- Structure
- Type I transmembrane receptor and member of the TNF receptor superfamily that contains 4 TNF receptor domains; predicted molecular weight approximately 64 kD
- Distribution
-
Highly expressed on Hodgkins and Reed-Sternberg cells and activated, but not resting, T cells and B cells.
- Function
- Signaling through CD30 is thought to limit the proliferative potential of autoreactive CD8 effector T cells and protect against autoimmunity.
- Interaction
- TRAF1, TRAF2, TRAF3, TRAF5, NPM-ALK, TRAF-interacting protein, CD30 ligand (CD153)
- Ligand/Receptor
- CD30 Ligand (CD153)
- Cell Type
- B cells, Embryonic Stem Cells, Tregs
- Biology Area
- Immunology, Stem Cells
- Molecular Family
- CD Molecules
- Antigen References
-
1. Durkop H, et al. 1992. Cell 68:421.
2. Aizawa S, et al. 1997. J. Biol. Chem. 272:2042.
3. Stein H, et al. 1982. Int. J. Cancer 30:445.
- Gene ID
- 943 View all products for this Gene ID
- UniProt
- View information about CD30 on UniProt.org
