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首页 > 抗体蛋白 > 抗体
Biotin anti-mouse CD144 (VE-cadherin) Antibody
产品名称：
Biotin anti-mouse CD144 (VE-cadherin) Antibody
产品类别：
抗体
产品编号：
138008
产品应用：
138008
[价格]
规格 价格 库存
100µg ￥ 4020 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
VE-cadherin-Ig fusion protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone BV13 recognizes an epitope between aa 45 and 56, and has a binding affinity of 5-15 nM5. Additional reported applications (for relevant formats) include: Western blotting1, blocking of cell interactions in vivo1, and immunofluorescence microscopy?staining4.

Application References

(PubMed link indicates BioLegend citation)
  1. Corada M, et al. 1999. P. Natl. Acad. Sci. USA 96:9815. (WB, Block)
  2. Liao F, et al. 2000. Cancer Res. 60:6805. (FC)
  3. Crosby CV, et al. 2005. Blood 105:2771. (FC)
  4. Liao F, et al. 2002. Cancer Res. 62:2567. (IF)
  5. May C, et al. 2005. Blood 105:4337. (epitope)
Product Citations
  1. Corey D, et al. 2016. Cancer Res . 76: 1348 - 1353. PubMed
RRID
AB_10641138 (BioLegend Cat. No. 138008)

Antigen Details

Structure
A 120 kD member of type II Cadherin family
Distribution

Endothelial cells

Function
Involved in endothelial cell survival, migration, contact-dependent growth inhibition, and hemophilic adhesion
Ligand/Receptor
CD144
Cell Type
Endothelial cells, Mesenchymal Stem Cells
Biology Area
Cell Biology, Immunology, Innate Immunity, Neuroscience, Stem Cells, Synaptic Biology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Allport JR, et al. 2002. J. Leukocyte Biol. 71:821.
2. Hirashima M, et al. 2009. Blood 93:1253.
3. Matsuyoshi N, et al. 1997. Proc. Assoc. Am. Physicians 109:362.
4. Matsumura K, et al. 2003. Blood 101:1367.
5. Hirashima M, et al. 2009. Blood 101:2261.
6. Gotsch U, et al. 1997. J. Cell Sci. 110:583.
7. Kataoka H, et al. 1997. Dev. Growth Differ. 39:729.

Gene ID
12562 View all products for this Gene ID
UniProt
View information about CD144 on UniProt.org

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