APC anti-mouse CD144 (VE-cadherin) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 1644	1

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Rat

Immunogen

VE-cadherin-Ig fusion protein

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.

Concentration

0.2 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.06 ?g per million cells in 100 ?l volume.? It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser

Red Laser (633 nm)

Application Notes

Clone BV13 recognizes an epitope between aa 45 and 56, and has a binding affinity of 5-15 nM⁵. Additional reported applications (for relevant formats) include: Western blotting¹, blocking of cell interactions in vivo¹, and immunofluorescence microscopy^?staining⁴.

Application References (PubMed link indicates BioLegend citation)

Corada M, et al. 1999. P. Natl. Acad. Sci. USA 96:9815. (WB, Block)
Liao F, et al. 2000. Cancer Res. 60:6805. (FC)
Crosby CV, et al. 2005. Blood 105:2771. (FC)
Liao F, et al. 2002. Cancer Res. 62:2567. (IF)
May C, et al. 2005. Blood 105:4337. (epitope)

Product Citations

Jurkin J, et al. 2016. J Allergy Clin Immunol. S0091-6749(16)31121-6. PubMed
Bibli SI, et al. 2020. Redox Biol. 28:101379. PubMed
Liu D, et al. 2021. JCI Insight. 6:. PubMed
Park M, et al. 2021. BMB Rep. 54:470. PubMed
Dieterich LC, et al. 2019. International Journal of Cancer. 145(10):2804-2815. PubMed
Ni F, et al. 2019. Cell Stem Cell. 24:608. PubMed
Geis T, et al. 2014. Exp Cell Res. 331:46. PubMed
Ye P, et al. 2022. Front Cardiovasc Med. 8:810477. PubMed
Gomez I, et al. 2020. Nat Commun. 11:214. PubMed
Ballesteros I, et al. 2020. Cell. 183(5):1282-1297.e18. PubMed
Singhal P, et al. 2016. Proc Natl Acad Sci U S A. 113: 122 - 127. PubMed

RRID

AB_10679039 (BioLegend Cat. No. 138011) AB_10680420 (BioLegend Cat. No. 138012)

Antigen Details

Structure: A 120 kD member of type II Cadherin family
Distribution: Endothelial cells
Function: Involved in endothelial cell survival, migration, contact-dependent growth inhibition, and hemophilic adhesion
Ligand/Receptor: CD144
Cell Type: Endothelial cells, Mesenchymal Stem Cells
Biology Area: Cell Biology, Immunology, Innate Immunity, Neuroscience, Stem Cells, Synaptic Biology
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Allport JR, et al. 2002. J. Leukocyte Biol. 71:821.
2. Hirashima M, et al. 2009. Blood 93:1253.
3. Matsuyoshi N, et al. 1997. Proc. Assoc. Am. Physicians 109:362.
4. Matsumura K, et al. 2003. Blood 101:1367.
5. Hirashima M, et al. 2009. Blood 101:2261.
6. Gotsch U, et al. 1997. J. Cell Sci. 110:583.
7. Kataoka H, et al. 1997. Dev. Growth Differ. 39:729.
Gene ID: 12562 View all products for this Gene ID
UniProt: View information about CD144 on UniProt.org

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