APC anti-human CD135 (Flt-3/Flk-2) Antibody
- 产品名称：
- APC anti-human CD135 (Flt-3/Flk-2) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 313307
- 产品应用：
- 313307
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1788 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- BV-173 pro-B cell line
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Product Citations
-
- Montefiori LE, et al. 2021. Cancer Discov. 11:2846. PubMed
- Brenet F, et al. 2013. J Exp Med. 210:623. PubMed
- Cao Z, et al. 2021. Molecular Cell. 81(17):3604-3622.e10. PubMed
- RRID
- AB_314992 (BioLegend Cat. No. 313307) AB_2104835 (BioLegend Cat. No. 313308)
- Structure
- Member of the immunoglobulin supergene family, type 3 tyrosine kinase receptor; 130-160 kD
- Distribution
-
Expressed on CD34+ hematopoietic stem cells, myelomonocytic progenitors, primitive B cell progenitors, and thymocytes. Also expressed on AML, ALL and CML-BC tumor cells
- Function
- Tyrosine kinase growth factor receptor involved in the growth and differentiation of primitive hematopoietic cells
- Ligand/Receptor
- FLT3 ligand
- Cell Type
- B cells, Hematopoietic stem and progenitors, Leukemia, Thymocytes
- Biology Area
- Cell Biology, Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors
- Antigen References
-
1. Rappold I, et al. 1997. Blood 90:111.
2. Rosnet O, et al. 1996. Acta Haematol. 95:218.
3. Rosnet O, et al. 1996. Leukemia 10:238.
4. Bertho JM, et al. 2000. Scand. J. Immunol. 52:53.
- Gene ID
- 2322 View all products for this Gene ID
- UniProt
- View information about CD135 on UniProt.org
