Purified anti-human CD11c (Maxpar® Ready) Anti
- 产品名称：
- Purified anti-human CD11c (Maxpar® Ready) Anti
- 产品类别：
- 抗体
- 产品编号：
- 337221
- 产品应用：
- 337221
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 1.0 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
CyTOF? - Verified
- Recommended Usage
This product is suitable for use with the?Maxpar? Metal Labeling Kits.?For metal labeling using Maxpar? Ready antibodies,?proceed directly to the step to Partially Reduce the Antibody by adding 100 ?l of Maxpar? Ready antibody to 100 ?l of 4 mM TCEP-R in a 50 kDa filter and continue with the protocol. Always refer to the latest version of Maxpar? User Guide when conjugating Maxpar? Ready antibodies.
- Application Notes
Clone Bu15 has a different binding epitope than clone 3.9. The binding of Bu15 with CD11c is divalent cation independent. Additional reported applications (for the relevant formats of this clone) include: inhibition of CD11c mediated adhesion and stimulation of chemokine production by monocytes.
- Additional Product Notes
Maxpar? is a registered trademark of Standard BioTools Inc.
- Application References
(PubMed link indicates BioLegend citation) -
- Sadhu C, et al. 2008. J. Immunoass. Immunoch. 29:42.
- Rezzonico R, et al. 2001. Blood 97:2932.
- Sadhu C, et al. 2007. J. Leukoc. Biol. 81:1395.
- Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
- Product Citations
-
- Gadalla R, et al. 2022. STAR Protoc. 3:101643. PubMed
- Wagner J et al. 2019. Cell. 177(5):1330-1345 . PubMed
- Stras SF, et al. 2020. Developmental Cell. 51(3):357-373.e5.. PubMed
- Gide TN, et al. 2019. Cancer Cell. 35:238. PubMed
- Dumas AA, et al. 2020. EMBO J. 39:e103790. PubMed
- Schulte–Schrepping J, et al. 2020. Cell. 182(6):1419-1440. PubMed
- Cheung P, et al. 2018. Cell. 173:1385. PubMed
- Jordan S, et al. 2020. Cell. 178(5):1102-1114.e17.. PubMed
- Georg P, et al. 2022. Cell. 185:493. PubMed
- Wimmers F, et al. 2021. Cell. 184:3915. PubMed
- RRID
- AB_2562834 (BioLegend Cat. No. 337221)
- Structure
- Integrin, type I transmembrane glycoprotein, associates with integrin β2 (CD18), 145-150 kD
- Distribution
-
Myeloid, dendritic cells, NK cells, B cells and T cell subsets
- Function
- Adhesion, CTL killing Ligand Receptor: CD54, fibrinogen, iC3b, ICAM-1, ICAM-4 Antigen
- Cell Type
- B cells, Dendritic cells, Neutrophils, NK cells, T cells
- Biology Area
- Cell Biology, Costimulatory Molecules, Immunology, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Petty H. 1996. Immunol. Today 17:209.
2. Springer T. 1994. Cell 76:301.
3. Ihanus E, et al. 2007. Blood 109:802-810.
- Gene ID
- 3687 View all products for this Gene ID
- UniProt
- View information about CD11c on UniProt.org
