PE/Cyanine7 anti-human CD11c Antibody
- 产品名称：
- PE/Cyanine7 anti-human CD11c Antibody
- 产品类别：
- 抗体
- 产品编号：
- 337215
- 产品应用：
- 337215
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1980 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Clone Bu15 has a different binding epitope than clone 3.9. The binding of Bu15 with CD11c is divalent cation independent. Additional reported applications (for the relevant formats of this clone) include: inhibition of CD11c mediated adhesion and stimulation of chemokine production by monocytes.
- Additional Product Notes
- BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
- Application References
(PubMed link indicates BioLegend citation) -
- Sadhu C, et al. 2008. J. Immunoass. Immunoch. 29:42.
- Rezzonico R, et al. 2001. Blood 97:2932.
- Sadhu C, et al. 2007. J. Leukoc. Biol. 81:1395.
- Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
- Product Citations
-
- Alcántara‐Hernández M et al. 2017. Immunity. 47(6):1037-1050 . PubMed
- Fournier N, et al. 2018. MAbs. 10:651. PubMed
- Oostindie SC, et al. 2022. Nat Biotechnol. :. PubMed
- Hagen SH, et al. 2020. Cell Rep. 33:108485. PubMed
- Sutton HJ, et al. 2021. Cell Reports. 34(6):108684. PubMed
- Tang-Huau TL, et al. 2018. Nat Commun. 9:2570. PubMed
- Bourdely P, et al. 2020. Immunity. 53(2):335-352. PubMed
- Leylek R, et al. 2019. Cell Rep. 29:3736. PubMed
- Brown CC, et al. 2020. Cell. 179(4):846-863.e24.. PubMed
- Alhaj Hussen K, et al. 2017. Immunity. 47:680. PubMed
- Autenrieth S, et al. 2015. Clin Transl Immunology. 4:50. PubMed
- Hagen SH, et al. 2021. STAR Protocols. 2(3):100641. PubMed
- Richardson JR, et al. 2018. Front Immunol. 2.182638889. PubMed
- Prendergast B, et al. 2013. Brain Behav Immun. 32:104. PubMed
- Mackroth M, et al. 2016. PLoS Pathog. 12:e1005909. PubMed
- Kurilin V, et al. 2022. Mol Clin Oncol. 17:155. PubMed
- Lahaye X et al. 2018. Cell. 175(2):488-501 . PubMed
- RRID
- AB_2129791 (BioLegend Cat. No. 337215) AB_2129790 (BioLegend Cat. No. 337216)
- Structure
- Integrin, type I transmembrane glycoprotein, associates with integrin β2 (CD18), 145-150 kD
- Distribution
-
Myeloid, dendritic cells, NK cells, B cells and T cell subsets
- Function
- Adhesion, CTL killing Ligand Receptor: CD54, fibrinogen, iC3b, ICAM-1, ICAM-4 Antigen
- Cell Type
- B cells, Dendritic cells, Neutrophils, NK cells, T cells
- Biology Area
- Cell Biology, Costimulatory Molecules, Immunology, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Petty H. 1996. Immunol. Today 17:209.
2. Springer T. 1994. Cell 76:301.
3. Ihanus E, et al. 2007. Blood 109:802-810.
- Gene ID
- 3687 View all products for this Gene ID
- UniProt
- View information about CD11c on UniProt.org
