APC/Cyanine7 anti-human CD11c Antibody
- 产品名称：
- APC/Cyanine7 anti-human CD11c Antibody
- 产品类别：
- 抗体
- 产品编号：
- 337217
- 产品应用：
- 337217
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2052 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with APC/Cyanine7 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Clone Bu15 has a different binding epitope than clone 3.9. The binding of Bu15 with CD11c is divalent cation independent. Additional reported applications (for the relevant formats of this clone) include: inhibition of CD11c mediated adhesion and stimulation of chemokine production by monocytes.
- Additional Product Notes
- BioLegend is in the process of converting the name APC/Cy7 to APC/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our APC/Cyanine7 products. Please contact Technical Service if you have any questions.
- Application References
(PubMed link indicates BioLegend citation) -
- Sadhu C, et al. 2008. J. Immunoass. Immunoch. 29:42.
- Rezzonico R, et al. 2001. Blood 97:2932.
- Sadhu C, et al. 2007. J. Leukoc. Biol. 81:1395.
- Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
- Product Citations
-
- De Hert E, et al. 2022. Int J Mol Sci. 23:. PubMed
- Cavalli G, et al. 2016. Proc Natl Acad Sci U S A. 113: 1363 - 1368. PubMed
- Liu C, et al. 2021. Cell Res. 31:1106. PubMed
- Canavan M, et al. 2018. JCI Insight. 3:. PubMed
- Izquierdo-Useros N, et al. 2012. PLoS One. 10:e1001315. PubMed
- Forbester JL, et al. 2020. J Virol. 94:. PubMed
- Wouters K, et al. 2017. Sci Rep. 7:42665. PubMed
- Grandclaudon M, et al. 2019. Cell. 179:432. PubMed
- Kaur A, et al. 2019. Cancer Discov. 9:64. PubMed
- Fredriksson K, et al. 2014. J Immunol. 192:4497. PubMed
- Richardson JR, et al. 2018. Front Immunol. 2.182638889. PubMed
- Verboven K, et al. 2018. Sci Rep. 8:4677. PubMed
- Zhang X, et al. 2021. Nat Commun. 12:4536. PubMed
- Céspedes PF, et al. 2022. Nat Commun. 13:3460. PubMed
- Jardine L, et al. 2019. Nat Commun. 10:1999. PubMed
- Ceglia V, et al. 2021. J Immunol. 207:2060. PubMed
- Koh WH, et al. 2020. STAR Protoc. 1:100203. PubMed
- Milne P, et al. 2015. Blood. 125:470. PubMed
- Zimmermann M, et al. 2019. Front Immunol. 10:829. PubMed
- Cytlak U, et al. 2020. Immunity. 53(2):353-370. PubMed
- Ceglia V, et al. 2022. Front Immunol. 12:786144. PubMed
- RRID
- AB_10661724 (BioLegend Cat. No. 337217) AB_10662746 (BioLegend Cat. No. 337218)
- Structure
- Integrin, type I transmembrane glycoprotein, associates with integrin β2 (CD18), 145-150 kD
- Distribution
-
Myeloid, dendritic cells, NK cells, B cells and T cell subsets
- Function
- Adhesion, CTL killing Ligand Receptor: CD54, fibrinogen, iC3b, ICAM-1, ICAM-4 Antigen
- Cell Type
- B cells, Dendritic cells, Neutrophils, NK cells, T cells
- Biology Area
- Cell Biology, Costimulatory Molecules, Immunology, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Petty H. 1996. Immunol. Today 17:209.
2. Springer T. 1994. Cell 76:301.
3. Ihanus E, et al. 2007. Blood 109:802-810.
- Gene ID
- 3687 View all products for this Gene ID
- UniProt
- View information about CD11c on UniProt.org
