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Purified anti-mouse CD157 (BST-1) Antibody
产品名称:
Purified anti-mouse CD157 (BST-1) Antibody
产品类别:
抗体
产品编号:
140202
产品应用:
140202
[价格]
规格 价格 库存
100µg ¥ 2148 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Murine pre-B cell line 18.81
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. McNagny KM, et al. 1988. J. Immunol. 141:2551. (FC)
RRID
AB_10639943 (BioLegend Cat. No. 140202)

Antigen Details

Structure
Member of the ADP-ribosyl cyclase family, ectoenzyme, 40-46 kD, glycosyl-phosphatidylinositol (GPI)- anchored membrane protein, present on the cell surface as a homodimer
Distribution

Expressed by endothelial cells, follicular dendritic cells, cells from the myeloid lineage, and T and B cell precursors prior to the rearrangement of the antigen receptor. Expressed in many cell types from different tissues like the bone marrow, spleen, thymus, lung, kidney and heart.

Function
Synthesizes cyclic ADP-ribose (cADPR), a second messenger that elicits calcium release from intracellular stores.
Cell Type
B cells, Dendritic cells, Endothelial cells, T cells
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules
Antigen References

1. Yamamoto-Katayama S, et al. 2002. J. Mol. Biol. 310:711.
2. Funaro A, et al. 2009. Front. Biosci. 14:929.
3. Malavasi F, et al. 2006. Mol. Med. 12:334.
4. Vicari AP, et al. 1996. Int. Immunol. 8:183.

Gene ID
12182 View all products for this Gene ID
UniProt
View information about CD157 on UniProt.org

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