Purified anti-human CD294 (CRTH2) Antibody
- 产品名称：
- Purified anti-human CD294 (CRTH2) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 350102
- 产品应用：
- 350102
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Rat cell line TART/B19-12.10 transfected with human CRTH2
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This product is sold under license agreement with BML, Inc for research use only.
- Application References
(PubMed link indicates BioLegend citation) -
- Nagata K, et al. 1999. J. Immunol. 162:1278. (FC)
- De Fanis U, et al. 2007. Blood 109:4343. (FC)
- Tsuda H, et al. 2001. Clin. Exp. Immunol. 123:105. (FC)
- Hamada K, et al. 2004. Allergology International 53:179. (FC)
- Product Citations
-
- Friebel E, et al. 2020. Cell. 181(7):1626-1642.e20. PubMed
- Stras SF, et al. 2020. Developmental Cell. 51(3):357-373.e5.. PubMed
- van Montfoort N, et al. 2018. Cell. 175:1744. PubMed
- Roussel M, et al. 2021. Cell Reports Medicine. 2(6):100291. PubMed
- Kim ML, et al. 2018. Circulation. 138:2648. PubMed
- Dutertre CA, et al. 2020. Immunity. 51(3):573-589.e8.. PubMed
- RRID
- AB_10639863 (BioLegend Cat. No. 350102)
- Structure
- Seven-transmembrane protein coupled with G proteins
- Distribution
-
Effector T helper 2 (Th2) cells, eosinophils, basophils
- Function
- Chemotaxis of eosinophils, basophils and Th2 cells, prevention of apoptosis in Th2 cells
- Interaction
- Heterotrimeric G proteins
- Ligand/Receptor
- Prostaglandin D2
- Cell Type
- Basophils, Eosinophils, Th2
- Biology Area
- Cell Biology, Cell Motility/Cytoskeleton/Structure, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Luster AD and Tager AM. 2004. Nat. Rev. Immunol. 4:711.
2. Monneret G, et al. 2001. Blood 98:1942.
3. Xue L, et al. 2009. J. Immunol. 182:7580.
4. Schratl P, et al. 2007. J. Immunol. 179:4792.
- Gene ID
- 11251 View all products for this Gene ID
- UniProt
- View information about CD294 on UniProt.org
