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Alexa Fluor® 647 anti-human CD294 (CRTH2) Anti
产品名称:
Alexa Fluor® 647 anti-human CD294 (CRTH2) Anti
产品类别:
抗体
产品编号:
350103
产品应用:
350103
[价格]
规格 价格 库存
25tests ¥ 1272 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Rat cell line TART/B19-12.10 transfected with human CRTH2
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 647 under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

* Alexa Fluor? 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm.


Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

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Excitation Laser
Red Laser (633 nm)
Application Notes

This product is sold under license agreement with BML, Inc for research use only.

Application References

(PubMed link indicates BioLegend citation)
  1. Nagata K, et al. 1999. J. Immunol. 162:1278. (FC)
  2. De Fanis U, et al. 2007. Blood 109:4343. (FC)
  3. Tsuda H, et al. 2001. Clin. Exp. Immunol. 123:105. (FC)
  4. Hamada K, et al. 2004. Allergology International 53:179. (FC)
Product Citations
  1. Witkowski M, et al. 2021. Nature. 600:295. PubMed
  2. Wright AKA, et al. 2017. J Allergy Clin Immunol. 140:1430. PubMed
  3. Vijayakumar B, et al. 2022. Immunity. . PubMed
  4. Silver J, et al. 2020. Methods Mol Biol. 2121:115. PubMed
  5. Kato M, et al. 2021. PLoS One. 16:e0252116. PubMed
RRID
AB_10640066 (BioLegend Cat. No. 350103) AB_10642025 (BioLegend Cat. No. 350104)

Antigen Details

Structure
Seven-transmembrane protein coupled with G proteins
Distribution

Effector T helper 2 (Th2) cells, eosinophils, basophils

Function
Chemotaxis of eosinophils, basophils and Th2 cells, prevention of apoptosis in Th2 cells
Interaction
Heterotrimeric G proteins
Ligand/Receptor
Prostaglandin D2
Cell Type
Th2, Eosinophils, Basophils
Biology Area
Cell Biology, Cell Motility/Cytoskeleton/Structure, Immunology
Molecular Family
CD Molecules
Antigen References

1. Luster AD and Tager AM. 2004. Nat. Rev. Immunol. 4:711.
2. Monneret G, et al. 2001. Blood 98:1942.
3. Xue L, et al. 2009. J. Immunol. 182:7580.
4. Schratl P, et al. 2007. J. Immunol. 179:4792.

Gene ID
11251 View all products for this Gene ID
UniProt
View information about CD294 on UniProt.org

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