Purified anti-human CD48 Antibody
- 产品名称：
- Purified anti-human CD48 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 336702
- 产品应用：
- 336702
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IP - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, it is recommended to use at ≤ 2.0 ?g per 106 cells in 100 ?l volume or 100 ?l of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats) include: immunoprecipitation.
- Application References
(PubMed link indicates BioLegend citation) -
- Kishimoto T, et al. 1997. Leucocyte Typing VI:White Cell Differentiation Antigens. Garland Publishing Inc.
- Wang R, et al. 2012. J. Leukoc Biol. 91:299. PubMed
- Product Citations
-
- Sander J et al. 2017. Immunity. 47(6):1051-1066 . PubMed
- Dinh HQ, et al. 2020. Immunity. 53(2):319-334.e6. PubMed
- RRID
- AB_1227561 (BioLegend Cat. No. 336702)
- Structure
- CD2 family, contains 2 IgSF domains, GPI-membrane anchored, 40-47 kD
- Distribution
-
Widely expressed on hematopoietic cells except granulocytes, platelets, and erythrocytes. Increased on T and B cells after activation
- Function
- Contributes to T cell antigen recognition
- Ligand/Receptor
- CD2
- Cell Targets
- Lck, Fyn interact with cytoplasmic domain
- Cell Type
- B cells
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
- Fisher RC and Thorley-Lawson DA. 1991. Mol. Cell. Biol. 11:1614.
- Korinek V, et al. 1991. Immunogenetics 33:108.
- Leukocyte Typing IV. Knapp W, et al. (Eds) Oxford University Press (1989)
- Leukocyte Typing V. Schlossman S, et al. (Eds) Oxford University Press (1995)
- Gene ID
- 962 View all products for this Gene ID
- UniProt
- View information about CD48 on UniProt.org
