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PE anti-human CD44 Antibody
产品名称:
PE anti-human CD44 Antibody
产品类别:
抗体
产品编号:
338807
产品应用:
338807
[价格]
规格 价格 库存
25tests ¥ 1548 1

产品详情

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Cynomolgus, Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Normal human PBL
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Kishimoto T, et al. eds. 1997 Leucocyte Typing VI:White Cell Differentiation Antigen. Garland Publishing Inc.
Product Citations
  1. Qiao X, et al. 2021. Elife. 10: . PubMed
  2. Park J, et al. 2021. Exp Ther Med. 22:808. PubMed
  3. Diessner J, et al. 2014. Cell Death Dis. 5:1149. PubMed
  4. Liu MY, et al. 2019. Oncol Lett. 18:3664. PubMed
  5. Palamides P, et al. 2016. Dis Model Mech. 9: 985 - 997. PubMed
  6. Zeng F, et al. 2021. Cancer Gene Therapy. . PubMed
  7. Murata K, et al. 2019. Oncol Lett. 17:5830. PubMed
  8. Floyd T, et al. 2011. J Immunol. 186:2033. PubMed
  9. Meng YM, et al. 2021. Nat Commun. 12:6011. PubMed
  10. Cromwell EF, et al. 2022. SLAS Discov. . PubMed
  11. Kolodziej M, et al. 2019. Adipocyte. 0.509722222. PubMed
  12. Ross NT, et al. 2020. Nature Chemical Biology. 16(1):50-59.. PubMed
  13. Kolchakova D, et al. 2021. Biomolecules. 11:. PubMed
  14. Jiang L, et al. 2020. Cell. 183(5):1219-1233.e18. PubMed
  15. Labedz-Maslowska A, et al. 2020. Int J Mol Sci. 21:. PubMed
  16. Liu Y, et al. 2018. Chin J Cancer. 37:2. PubMed
  17. Wei X, et al. 2019. Int J Mol Med. 44:1425. PubMed
  18. Wang G, et al. 2018. Int J Mol Med. 41:791. PubMed
RRID
AB_2260222 (BioLegend Cat. No. 338807) AB_2076578 (BioLegend Cat. No. 338808)

Antigen Details

Structure
Variable splicing of CD44 gene generates many CD44 isoforms, 85 kD
Distribution

All leukocytes, epithelial cells, endothelial cells, hepatocytes, mesenchymal cells

Function
Leukocyte attachment and rolling on endothelial cells, stromal cells and ECM
Ligand/Receptor
Hyaluronan, MIP-1β, fibronectin, collagen
Cell Type
Endothelial cells, Epithelial cells, Leukocytes, Mesenchymal cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Immunology, Stem Cells
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Haynes BF, et al. 1991. Cancer Cells 3:347.
3. Goldstein LA, et al. 1989. Cell 56:1063.
4. Mikecz K, et al. 1995. Nat. Med. 1:558.

Gene ID
960 View all products for this Gene ID
UniProt
View information about CD44 on UniProt.org

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