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APC anti-human CD44 Antibody
产品名称:
APC anti-human CD44 Antibody
产品类别:
抗体
产品编号:
338805
产品应用:
338805
[价格]
规格 价格 库存
25tests ¥ 1788 1

产品详情

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Cynomolgus, Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Normal human PBL
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Red Laser (633 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Kishimoto T, et al. eds. 1997 Leucocyte Typing VI:White Cell Differentiation Antigen. Garland Publishing Inc.
Product Citations
  1. Wang C, et al. 2020. British Journal of Pharmacology. 177(13):3009-3023. PubMed
  2. Grayson KA, et al. 2021. Mol Cancer Ther. 20:833. PubMed
  3. Weigert A, et al. 2022. Nat Commun. 13:6078. PubMed
  4. Deshmukh A, et al. 2018. Cancers (Basel). 10. PubMed
  5. Wang X, et al. 2020. Front Oncol. 1.083333333. PubMed
  6. Parker KA, et al. 2021. Mol Cancer Res. 19:2068. PubMed
  7. Ma J, et al. 2021. Curr Protoc. 1:e144. PubMed
  8. Ragni E, et al. 2022. Biomolecules. 12:. PubMed
  9. Jang G, et al. 2022. NPJ Genom Med. 7:63. PubMed
  10. Bryson BL, et al. 2021. Mol Cancer Res. 19:651. PubMed
  11. Hyun Hee Lee, Vanessa Bellat, Benedict Law 2017. PLoS One. 12(2):e0171044. PubMed
  12. Adnani L, et al. 2022. Nat Commun. 13:5494. PubMed
  13. Bugalho A, et al. 2013. Clin Lung Cancer. 14:704. PubMed
  14. Kim M, et al. 2017. Cytokine. 10.1016/j.cyto.2017.07.007. PubMed
  15. Grayson KA, et al. 2021. PLoS One. 16:e0246733. PubMed
  16. Gradiz R, et al. 2016. Sci Rep. 6:21648. PubMed
  17. Xu P, et al. 2020. Cancer Immunol Res. 8:1193. PubMed
  18. Cho JH, et al. 2021. Nat Commun. 12:792. PubMed
  19. Raman S, et al. 2021. Cell Reports Medicine. 2(7):100344. PubMed
  20. Beghelli D, et al. 2017. Oxid Med Cell Longev. 10.1155/2017/7468064. PubMed
  21. Luo HT, et al. 2021. NPJ Genom Med. 6:48. PubMed
  22. Lee CH, et al. 2018. Elife. 7:e32532. PubMed
  23. Papait A, et al. 2022. Front Immunol. 13:960909. PubMed
  24. Repas J, et al. 2021. Sci Rep. 11:21354. PubMed
RRID
AB_1501202 (BioLegend Cat. No. 338805) AB_1501195 (BioLegend Cat. No. 338806)

Antigen Details

Structure
Variable splicing of CD44 gene generates many CD44 isoforms, 85 kD
Distribution

All leukocytes, epithelial cells, endothelial cells, hepatocytes, mesenchymal cells

Function
Leukocyte attachment and rolling on endothelial cells, stromal cells and ECM
Ligand/Receptor
Hyaluronan, MIP-1β, fibronectin, collagen
Cell Type
Endothelial cells, Epithelial cells, Leukocytes, Mesenchymal cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Immunology, Stem Cells
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Haynes BF, et al. 1991. Cancer Cells 3:347.
3. Goldstein LA, et al. 1989. Cell 56:1063.
4. Mikecz K, et al. 1995. Nat. Med. 1:558.

Gene ID
960 View all products for this Gene ID
UniProt
View information about CD44 on UniProt.org

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