Alexa Fluor® 647 anti-human CD134 (OX40) Antib
- 产品名称：
- Alexa Fluor® 647 anti-human CD134 (OX40) Antib
- 产品类别：
- 抗体
- 产品编号：
- 350017
- 产品应用：
- 350017
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1764 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- Chimpanzee
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- HTLV 1-transformed HUT 102 cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 647 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
* Alexa Fluor? 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm.
Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.
View full statement regarding label licenses - Excitation Laser
- Red Laser (633 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: Western blotting1, immunoprecipitation1, immunohistochemical staining2,3of paraffin embedded7 and frozen tissue sections, ELISA4, and functional assay5. The LEAF? or Ultra-LEAF? purified antibody is recommended for functional assays (contact our custom solutions team).
- Application References
(PubMed link indicates BioLegend citation) -
- Latza U, et al. 1994. Eur. J. Immunol. 24:677. (WB, IP)
- Durkop H, et al. 1995. Brit. J. Haematol. 91:927. (IHC)
- Durkop H, et al. 1997. Brit. J. Haematol. 98:863. (IHC)
- Willett B, et al. 2007. J. Virol. 81:9665. (ELISA)
- Li M and Zhang Y. et al. 2005. Cell. Mol. Immunol. 2:467. (FA)
- Gloviczki ML, et al. 2012. Clin. J. Am. Soc. Nephrol. 8:546. PubMed
- Domingos PL, et al. 2012. An. Bras. Dermatol. 87:851. (IHC)
- Product Citations
-
- Siegemund M, et al. 2021. Front Pharmacol. 12:759337. PubMed
- Geuijen C, et al. 2021. Nat Commun. 12:4445. PubMed
- Kuo HH, et al. 2018. Immunity. 48:1183. PubMed
- Del Alcazar D, et al. 2019. Cell Rep. 28:3047. PubMed
- Nguyen J, et al. 2021. Mol Syst Biol. 17:e10560. PubMed
- RRID
- AB_2571937 (BioLegend Cat. No. 350017) AB_2571938 (BioLegend Cat. No. 350018)
- Structure
- 50 kD, TNF receptor family
- Distribution
-
Activated T cells
- Function
- Receptor for OX40 ligand, co-stimulatory signal for T cell proliferation and survival.
- Ligand/Receptor
- OX40L (CD252)
- Cell Type
- T cells, Tregs
- Biology Area
- Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules, Immune Checkpoint Receptors
- Antigen References
-
1. Smith CA, et al. 1994. Cell. 76:959.
2. Chen AL, et al. 1999. Immunity. 11:689.
3. Croft M. 2010. Annu. Rev. Immunol. 28:57.
4. Ruby CE, et al. 2009. J. Immunol. 183:5079.
5. Klinger M, et al. 2009. J. Immunol. 182:4581.
- Gene ID
- 7293 View all products for this Gene ID
- UniProt
- View information about CD134 on UniProt.org
