FITC anti-human CD25 Antibody
- 产品名称：
- FITC anti-human CD25 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 302603
- 产品应用：
- 302603
- Verified Reactivity
- Human
- Reported Reactivity
- Baboon, Chimpanzee, Cynomolgus, Pigtailed Macaque, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
- Application Notes
Additional reported applications include: immunocytochemistry3.
- Application References
(PubMed link indicates BioLegend citation) -
- Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
- Kmieciak M, et al. 2009. J. Transl. Med. 7:89. (FC) PubMed
- Ernst CW, et al. 2007. Clin. Exp. Immunol. 148:271. (ICC) PubMed
- Product Citations
-
- Garcia–Perez JE, et al. 2019. Front Immunol. 10:998. PubMed
- Wang H, et al. 2020. Mol Oncol. 14:991. PubMed
- Kubo M, et al. 2018. Oncol Rep. 39:417. PubMed
- Pauthner MG, et al. 2019. Immunity. 50:241. PubMed
- Aqel SI, et al. 2021. JCI Insight. 6:e142376. PubMed
- Beswick E, et al. 2011. Infect Immun. 79:2737. PubMed
- Alissafi T, et al. 2020. Cell Metabolism. 32(4):591-604.e7. PubMed
- Turner AW, et al. 2020. ACS Infect Dis. 6:1719. PubMed
- Miles B, et al. 2015. Nat Commun. 6: 8608. PubMed
- Grivas A, et al. 2022. Front Immunol. 13:964274. PubMed
- Hassani M, et al. 2020. Iran Biomed J. 24:81. PubMed
- Liu H, et al. 2021. J Immunother Cancer. 9:. PubMed
- Qu K et al. 2017. Cancer cell. 32(1):27-41 . PubMed
- Dai Z, et al. 2022. Signal Transduct Target Ther. 7:85. PubMed
- Grigoriou M, et al. 2021. Cancer Immunol Res. 9:726. PubMed
- Cirelli KM et al. 2019. Cell. 177(5):1153-1171 . PubMed
- Rousso-Noori L, et al. 2021. Nat Commun. 12:3615. PubMed
- Kim ST, et al. 2021. J Immunother Cancer. 9:. PubMed
- Csomós K, et al. 2022. Nat Immunol. 23:1256. PubMed
- Rhijn I, et al. 2016. Proc Natl Acad Sci U S A. 113: 380 - 385. PubMed
- Ryba M, et al. 2011. Cytokine. 55:353. PubMed
- Jiang J, et al. 2016. Sci Rep. 6: 32320. PubMed
- Businaro R, et al. 2009. Atherosclerosis. 207:74. PubMed
- Yost KE, et al. 2019. Nat Med. 25:1251. PubMed
- Meniailo M, et al. 2017. Int Immunopharmacol. 10.1016/j.intimp.2017.06.023. PubMed
- RRID
- AB_314273 (BioLegend Cat. No. 302603) AB_314274 (BioLegend Cat. No. 302604)
- Structure
- Type I transmembrane glycoprotein, 55 kD
- Distribution
-
Activated T cells and B cells, monocytes/macrophages, Treg
- Function
- Associates with IL-2 receptor β (CD122) and γ chains (CD132) to form high affinity IL-2R complex
- Ligand/Receptor
- IL-2
- Cell Type
- B cells, Macrophages, Monocytes, T cells, Tregs
- Biology Area
- Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors
- Antigen References
-
1. Taniguchi T, et al. 1993. Cell 73:5.
2. Waldmann T. 1991. J. Biol. Chem. 266:2681.
- Gene ID
- 3559 View all products for this Gene ID
- UniProt
- View information about CD25 on UniProt.org
