APC anti-human CD25 Antibody
- 产品名称：
- APC anti-human CD25 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 302609
- 产品应用：
- 302609
- Verified Reactivity
- Human
- Reported Reactivity
- Baboon, Chimpanzee, Cynomolgus, Pigtailed Macaque, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Additional reported applications include: immunocytochemistry3.
- Application References
(PubMed link indicates BioLegend citation) -
- Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
- Kmieciak M, et al. 2009. J. Transl. Med. 7:89. (FC) PubMed
- Ernst CW, et al. 2007. Clin. Exp. Immunol. 148:271. (ICC) PubMed
- Product Citations
-
- Cao B, et al. 2022. Nat Commun. 13:6203. PubMed
- Otano I, et al. 2021. Nat Commun. 12:7296. PubMed
- Fuhrman C, et al. 2015. J Immunol. 195: 145 - 155. PubMed
- Goncharov MM, et al. 2022. Elife. 11:. PubMed
- Bednarski J, et al. 2016. J Exp Med. 213: 209 - 223. PubMed
- Pedersen JG, et al. 2021. Front Microbiol. 12:763030. PubMed
- Nixon CC, et al. 2020. Cell Reports Medicine. 578(7793):160-165. PubMed
- Dean JW, et al. 2020. J Autoimmun. 108:102417. PubMed
- Alenazy MF, et al. 2021. Sci Rep. 11:5629. PubMed
- Wang J, et al. 2020. Cell. 183:1264. PubMed
- Soodgupta D, et al. 2019. Cell Rep. 29:829. PubMed
- Juno JA, et al. 2020. Nat Med. 26:1428. PubMed
- Zhang B, et al. 2021. Nat Biomed Eng. 5:1288. PubMed
- Shevyrev D, et al. 2021. Exp Ther Med. 209:21. PubMed
- Cheng B, et al. 2022. Cancer Commun (Lond). 42:17. PubMed
- Walter F, et al. 2020. PLoS One. 15:e0239369. PubMed
- Cai J, et al. 2021. eLife. 10:00. PubMed
- Luo Y, et al. 2021. Nat Commun. 12:3913. PubMed
- Su X, et al. 2022. J Transl Med. 20:378. PubMed
- Chulpanova DS, et al. 2021. Biology (Basel). 10:. PubMed
- Roshani Asl E, et al. 2021. J Cell Physiol. 236:7071. PubMed
- Shemesh A, et al. 2022. J Exp Med. 219:. PubMed
- Ye Z, et al. 2021. NPJ Aging Mech Dis. 7:4. PubMed
- Martínez–Fábregas J, et al. 2019. Elife. 8:e49314. PubMed
- Wallstabe J, et al. 2020. ALTEX. 37:429. PubMed
- Pahl JHW, et al. 2018. Cancer Immunol Res. 0.609027778. PubMed
- Burke MT, et al. 2017. Transplant Direct. 3:e171. PubMed
- Chen J, et al. 2017. Sci Rep. 10.1038/s41598-017-11056-9. PubMed
- Winkler C, et al. 2021. JCI Insight. 6:. PubMed
- Zhu P, et al. 2022. Cell Commun Signal. 20:121. PubMed
- Hu JQ, et al. 2020. J Cancer. 3.409722222. PubMed
- Li Y, et al. 2022. Bioengineered. 13:4730. PubMed
- Trabanelli S, et al. 2014. J Immunol. 192:1231. PubMed
- Yamaguchi K, et al. 2018. Cancer Sci. 109:3032. PubMed
- RRID
- AB_314279 (BioLegend Cat. No. 302609) AB_314280 (BioLegend Cat. No. 302610)
- Structure
- Type I transmembrane glycoprotein, 55 kD
- Distribution
-
Activated T cells and B cells, monocytes/macrophages, Treg
- Function
- Associates with IL-2 receptor β (CD122) and γ chains (CD132) to form high affinity IL-2R complex
- Ligand/Receptor
- IL-2
- Cell Type
- B cells, Macrophages, Monocytes, T cells, Tregs
- Biology Area
- Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors
- Antigen References
-
1. Taniguchi T, et al. 1993. Cell 73:5.
2. Waldmann T. 1991. J. Biol. Chem. 266:2681.
- Gene ID
- 3559 View all products for this Gene ID
- UniProt
- View information about CD25 on UniProt.org
