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PE anti-mouse CD200R3 Antibody
产品名称:
PE anti-mouse CD200R3 Antibody
产品类别:
抗体
产品编号:
142306
产品应用:
142306
[价格]
规格 价格 库存
100µg ¥ 4164 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse primary basophils
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume.? It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Ba160 recognizes circulating and bone marrow basophils; it also recognizes a subset of mast cells in the peritoneal cavity and skin.

A single intravenous administration of 30 ?g of LEAF Ba160 to mice induces a dramatic reduction of basophil number in peripheral blood from day 1 to day 10. *Tested in the development stage.

Product Citations
  1. Kamijo S, et al. 2013. J Immunol. 190:4489. PubMed
RRID
AB_10917057 (BioLegend Cat. No. 142306)

Antigen Details

Structure
Immunoglobulin superfamily; disulfide-linked dimmer with positively charged amino acids in transmembrane; molecular weight is about ~38 kD or ~74 kD (reduced or non-reduced condition, respectively).
Distribution
Basophils in peripheral blood, bone marrow, spleen: mast cells in peritoneal cavity and skin.
Function
Transduce stimulatory signals.
Interaction
DAP12, DAP10, FcRγ, or CD3ζ
Cell Type
Basophils, Mast cells
Biology Area
Immunology, Inhibitory Molecules
Molecular Family
CD Molecules
Antigen References

1. Voehringer D, et al. 2004. J. Biol. Chem. 52:54117.
2. Kojima T, et al. 2007. J. Immunol. 179:7093.
3. Sato K, et al. 2009. Blood 113:4780.

Gene ID
74603 View all products for this Gene ID
UniProt
View information about CD200R3 on UniProt.org

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