PE anti-mouse CD200R3 Antibody
- 产品名称:
- PE anti-mouse CD200R3 Antibody
- 产品类别:
- 抗体
- 产品编号:
- 142306
- 产品应用:
- 142306
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse primary basophils
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume.? It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Ba160 recognizes circulating and bone marrow basophils; it also recognizes a subset of mast cells in the peritoneal cavity and skin.
A single intravenous administration of 30 ?g of LEAF Ba160 to mice induces a dramatic reduction of basophil number in peripheral blood from day 1 to day 10. *Tested in the development stage.
- Product Citations
-
- Kamijo S, et al. 2013. J Immunol. 190:4489. PubMed
- RRID
- AB_10917057 (BioLegend Cat. No. 142306)
- Structure
- Immunoglobulin superfamily; disulfide-linked dimmer with positively charged amino acids in transmembrane; molecular weight is about ~38 kD or ~74 kD (reduced or non-reduced condition, respectively).
- Distribution
- Basophils in peripheral blood, bone marrow, spleen: mast cells in peritoneal cavity and skin.
- Function
- Transduce stimulatory signals.
- Interaction
- DAP12, DAP10, FcRγ, or CD3ζ
- Cell Type
- Basophils, Mast cells
- Biology Area
- Immunology, Inhibitory Molecules
- Molecular Family
- CD Molecules
- Antigen References
-
1. Voehringer D, et al. 2004. J. Biol. Chem. 52:54117.
2. Kojima T, et al. 2007. J. Immunol. 179:7093.
3. Sato K, et al. 2009. Blood 113:4780.
- Gene ID
- 74603 View all products for this Gene ID
- UniProt
- View information about CD200R3 on UniProt.org