PE/Cyanine7 anti-mouse CD200R3 Antibody
- 产品名称:
- PE/Cyanine7 anti-mouse CD200R3 Antibody
- 产品类别:
- 抗体
- 产品编号:
- 142211
- 产品应用:
- 142211
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse primary basophils
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is = 0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Ba13 recognizes circulating and bone marrow basophils; it also recognizes a subset of mast cells in the peritoneal cavity and skin.?Additional reported applications (for the relevant formats) include: stimulation of bone marrow derived basophils to produce IL-4.
- Product Citations
-
- Wang F, et al. 2021. Cell. 184(2):422-440.e17. PubMed
- RRID
- AB_2814045 (BioLegend Cat. No. 142211) AB_2814046 (BioLegend Cat. No. 142212)
- Structure
- Immunoglobulin superfamily; disulfide-linked dimer with positively charge amino acids in transmembrane; molecular weight is about ~38 kD or ~74 kD (reduced or non-reduced conditions, respectively)
- Distribution
-
Basophils in peripheral blood, bone marrow, spleen; mast cells in peritoneal cavity and skin
- Function
- Transduce stimulatory signals
- Interaction
- DAP12, DAP10, FcRγ, or CD3ζ
- Cell Type
- Basophils, Mast cells
- Biology Area
- Immunology, Inhibitory Molecules
- Molecular Family
- CD Molecules
- Antigen References
-
1. Voehringer D, et al. 2004. J. Biol. Chem. 52:54117.
2. Kojima T, et al. 2007. J. Immunol. 179:7093.
3. Sato K, et al. 2009. Blood 113:4780.
- Gene ID
- 74603 View all products for this Gene ID
- UniProt
- View information about CD200R3 on UniProt.org