PE anti-human CD172b (SIRPβ) Antibody
- 产品名称：
- PE anti-human CD172b (SIRPβ) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 323906
- 产品应用：
- 323906
[价格]
| 规格 |
价格 |
库存 |
| 100tests |
￥ 3144 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- Baboon
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- NIH-3T3 cells transfected with SIRPbeta
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Seiffert M, et al. 2001. Blood 97:2741.
- Product Citations
-
- Sim J, et al. 2019. MAbs. 11:1036. PubMed
- Bsat M, et al. 2015. J Leukoc Biol. 98: 671 - 681. PubMed
- RRID
- AB_2254637 (BioLegend Cat. No. 323906)
- Structure
- Member of the signal regulatory protein family and immunoglobulin superfamily. Single pass transmembrane receptor with immunoglobulin-like domains; lacks cytoplasmic SHP-2 binding domain. Disulfide-linked homodimer, predicted MW ~43 kD.
- Distribution
-
Myeloid cells, monocytes, dendritic cells
- Function
- Negative regulation of tyrosine-kinase coupled signaling processes. Regulates neutrophil transepithelial migration
- Interaction
- DAP12 and Syk (through TYROBP)
- Cell Type
- Dendritic cells, Monocytes
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Kharitonenkov A, et al. 1997. Nature 386:181.
2. Tomasello E, et al. 2000. Eur. J. Immunol. 30:2147.
- Gene ID
- 10326 View all products for this Gene ID
- UniProt
- View information about CD172beta on UniProt.org
