PE anti-human CLEC1B (CLEC2) Antibody
- 产品名称：
- PE anti-human CLEC1B (CLEC2) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 372003
- 产品应用：
- 372003
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1836 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Extracellular region of CLEC1B (amino acids 68-229).
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunoprecipitation; inhibition of podoplanin and rhodocytin-mediated platelet activation.
- Application References
(PubMed link indicates BioLegend citation) -
- Gitz E, et al. 2014. Blood 124:2262.
- RRID
- AB_2650864 (BioLegend Cat. No. 372003) AB_2650865 (BioLegend Cat. No. 372004)
- Structure
- Type II transmembrane protein, 32 kD, homodimer, 1 hemITAM motif.
- Distribution
- Platelets, megakaryocytes; low expression on myeloid cells.
- Function
- Mediates platelet activation and aggregation; facilitates capture of HIV by platelets.
- Interaction
- Syk, PLC-g.
- Ligand/Receptor
- Rhodocytin, podoplanin.
- Cell Type
- Platelets, Megakaryocytes, Dendritic cells
- Biology Area
- Immunology
- Antigen References
-
1. Manne BK, et al. 2015. J. Biol. Chem. 290:11557.
2. Hughes CE, et al. 2013. J. Biol. Chem. 288:5127.
3. Pargui?a AF, et al. 2012. Blood 120:e117-26.
4. Osada M, et al. 2012. J. Biol. Chem. 287:22241.
- Gene ID
- 51266 View all products for this Gene ID
- UniProt
- View information about CLEC1B on UniProt.org
