PE anti-human EGFR Antibody
- 产品名称：
- PE anti-human EGFR Antibody
- 产品类别：
- 抗体
- 产品编号：
- 352903
- 产品应用：
- 352903
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1404 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Non-small cell lung cancer (NSCLC) cell line NCI-H322
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Yamaguchi M, et al. 2009. The 15th Annual Meeting Japan Society of Gene Therapy. p1056. Abstract 92.
- Product Citations
-
- Wang Y, et al. 2014. Biomaterials. 35:4297. PubMed
- Sreevalsan S, et al. 2020. EMBO Rep. 21:e50155. PubMed
- Kitamura Y, et al. 2021. Sci Adv. 7: . PubMed
- Halim L, et al. 2017. Cell Rep. 10.1016/j.celrep.2017.06.079. PubMed
- Wang JL, et al. 2022. Cancers (Basel). 14:. PubMed
- Lu T, et al. 2022. Nat Commun. 13:2576. PubMed
- Bak R and Proteus M. 2017. Cell Rep. 10.1016/j.celrep.2017.06.064. PubMed
- Jayasinghe MK, et al. 2022. Theranostics. 12:3288. PubMed
- Aldeghaither DS, et al. 2019. Cancer Immunol Res. 7:230. PubMed
- Carnevale J, et al. 2022. Nature. 609:174. PubMed
- Grass G, et al. 2013. J Biol Chem. 288:26089. PubMed
- Ahn S, et al. 2019. Cancer Immunol Res. 0.828472222. PubMed
- Edinger N, et al. 2016. PLoS One. 11: 0162321. PubMed
- Wing A, et al. 2018. Cancer Immunol Res. 6:605. PubMed
- Brohl AS, et al. 2021. Cell Rep. 37:110047. PubMed
- Okada R, et al. 2021. EBioMedicine. 67:103345. PubMed
- Han X, et al. 2017. Mol Ther. 10.1016/j.ymthe.2017.07.009. PubMed
- Jarantow S, et al. 2015. J Biol Chem. 290: 24689 - 24704. PubMed
- Li G, et al. 2021. Mol Ther Oncolytics. 22:507. PubMed
- Quijano-Rubio A, et al. 2022. Nat Biotechnol. Online ahead of print. PubMed
- Fischer A, et al. 2020. Toxins (Basel). 12:00. PubMed
- RRID
- AB_10898161 (BioLegend Cat. No. 352903) AB_10896794 (BioLegend Cat. No. 352904)
- Structure
- Member of the protein kinase superfamily; transmembrane glycoprotein; ligand binding induces dimerization and autophosphorylation
- Distribution
-
Epithelial cells and endothelial cells; frequently found in epithelial carcinomas
- Function
- Controls cell growth and differentiation
- Interaction
- MAPK, Akt, JNK
- Ligand/Receptor
- Members of the epidermal growth factor (EGF) family such as EGF, TGF-α, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor
- Cell Type
- Endothelial cells, Epithelial cells
- Biology Area
- Cell Biology, Cell Cycle/DNA Replication, Immunology, Innate Immunity, Neuroscience, Synaptic Biology
- Molecular Family
- CD Molecules, Growth Factors
- Antigen References
-
1. da Cunha Santos G, et al. 2011. Annu. Rev. Pathol. 6:49.
2. Gusterson BA and Hunter KD. 2009. Lancet Oncol. 10:522.
3. Mano M and Humblet Y. 2008. Nat. Clin. Pract. Oncol. 5:415.
4. Pao W and Chmielecki J. 2010. Nat. Rev. Cancer 10:760.
- Gene ID
- 1956 View all products for this Gene ID
- UniProt
- View information about EGFR on UniProt.org
