APC anti-human EGFR Antibody
- 产品名称：
- APC anti-human EGFR Antibody
- 产品类别：
- 抗体
- 产品编号：
- 352905
- 产品应用：
- 352905
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1500 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Non-small cell lung cancer (NSCLC) cell line NCI-H322
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Yamaguchi M, et al. 2009. The 15th Annual Meeting Japan Society of Gene Therapy. p1056. Abstract 92.
- Product Citations
-
- Sreevalsan S, et al. 2020. EMBO Rep. 21:e50155. PubMed
- Ho J, et al. 2019. Nat Commun. 10:2297. PubMed
- Halim L, et al. 2017. Cell Rep. 10.1016/j.celrep.2017.06.079. PubMed
- Xu X, et al. 2019. Cell Death Dis. 10:282. PubMed
- Yerneni SS, et al. 2021. MBio. 12:e0165721. PubMed
- Horii M, et al. 2021. Sci Rep. 11:5877. PubMed
- Bak R and Proteus M. 2017. Cell Rep. 10.1016/j.celrep.2017.06.064. PubMed
- Li Y, et al. 2013. Development. 140:3965. PubMed
- Niu M, et al. 2021. Nat Commun. 12:5919. PubMed
- Dong C, et al. 2022. Nat Commun. 13:2548. PubMed
- Horii M, et al. 2016. Proc Natl Acad Sci U S A. 113: E3882 - E3891. PubMed
- Morey R, et al. 2021. Front Cell Dev Biol. 9:702046. PubMed
- Yamaguchi Y, et al. 2022. J Immunother Cancer. 10:. PubMed
- Okita R, et al. 2015. PLoS One. 10: e0139809. PubMed
- Al-Akhrass H,et al. 2017. Nat Commun. . 10.1038/s41467-017-01172-5. PubMed
- Ludwig N, et al. 2020. Angiogenesis. 1.374305556. PubMed
- Khan SA, et al. 2021. Cell Reports. 35(11):109233. PubMed
- Song J, et al. 2021. Theranostics. 11:996. PubMed
- Dong YH, et al. 2018. Onco Targets Ther. 11:7053. PubMed
- Dong A, et al. 2015. J Biol Chem. 290:8016. PubMed
- Pasternack J, et al. 2014. J Nucl Med. 55:2012. PubMed
- RRID
- AB_11148943 (BioLegend Cat. No. 352905) AB_11150410 (BioLegend Cat. No. 352906)
- Structure
- Member of the protein kinase superfamily; transmembrane glycoprotein; ligand binding induces dimerization and autophosphorylation
- Distribution
-
Epithelial cells and endothelial cells; frequently found in epithelial carcinomas
- Function
- Controls cell growth and differentiation
- Interaction
- MAPK, Akt, JNK
- Ligand/Receptor
- Members of the epidermal growth factor (EGF) family such as EGF, TGF-α, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor
- Cell Type
- Endothelial cells, Epithelial cells
- Biology Area
- Cell Biology, Cell Cycle/DNA Replication, Immunology, Innate Immunity, Neuroscience, Synaptic Biology
- Molecular Family
- CD Molecules, Growth Factors
- Antigen References
-
1. da Cunha Santos G, et al. 2011. Annu. Rev. Pathol. 6:49.
2. Gusterson BA and Hunter KD. 2009. Lancet Oncol. 10:522.
3. Mano M and Humblet Y. 2008. Nat. Clin. Pract. Oncol. 5:415.
4. Pao W and Chmielecki J. 2010. Nat. Rev. Cancer 10:760.
- Gene ID
- 1956 View all products for this Gene ID
- UniProt
- View information about EGFR on UniProt.org
