Purified anti-mouse CD140b Antibody
- 产品名称：
- Purified anti-mouse CD140b Antibody
- 产品类别：
- 抗体
- 产品编号：
- 136002
- 产品应用：
- 136002
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse PDGFR-β-hIgG1 recombinant fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
WB, Block - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported (for the relevant formats) applications include: Western blotting and blocking function2. The LEAF? purified antibody is recommended for functional assays.
- Application References
(PubMed link indicates BioLegend citation) -
- Sano H, et al. 2001. Circulation 103:2955.
- Sano H, et al. 2002. Am. J. Pathol. 161:135. (Block)
- Product Citations
-
- McGowan SE, et al. 2018. Am J Physiol Lung Cell Mol Physiol. 315:L102. PubMed
- Kobayakawa K, et al. 2019. Sci Adv. 5:eaav5086. PubMed
- Iida Y, et al. 2020. J Immunother Cancer. 8:. PubMed
- Winter C, et al. 2018. Cell Metab. 28:175. PubMed
- RRID
- AB_1953332 (BioLegend Cat. No. 136002)
- Structure
- Beta chain of the platelet-derived growth factor receptor, a receptor tyrosine kinase that forms homo- or hetero-dimers on the surface after ligand binding.
- Distribution
-
Expressed on embryonic tissues and mesenchymal-derived cells of adult mouse.
- Function
- Play a role in wound healing and act as a chemoattractant for fibroblasts, smooth muscle cells, glial cells, monocytes and neutrophils.
- Ligand/Receptor
- PDGFs
- Cell Type
- Embryonic Stem Cells, Mesenchymal Stem Cells
- Biology Area
- Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers, Stem Cells
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors
- Antigen References
-
1. Soriano P, et al. 1994. Genes Dev. 8:1888
2. Takakura N, et al. 1996. J Invest Dermatol. 107:770
3. Yarden Y, et al. 1986. Nature 323:226
- Gene ID
- 18596 View all products for this Gene ID
- UniProt
- View information about CD140b on UniProt.org
