PE anti-mouse CD140b Antibody
- 产品名称：
- PE anti-mouse CD140b Antibody
- 产品类别：
- 抗体
- 产品编号：
- 136005
- 产品应用：
- 136005
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse PDGFR-β-hIgG1 recombinant fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported (for the relevant formats) applications include: Western blotting and blocking function2. The LEAF? purified antibody is recommended for functional assays.
- Application References
(PubMed link indicates BioLegend citation) -
- Sano H, et al. 2001. Circulation 103:2955.
- Sano H, et al. 2002. Am. J. Pathol. 161:135. (Block)
- Product Citations
-
- Su Q, et al. 2021. iScience. 24:103233. PubMed
- Higashi AY, et al. 2019. J Am Soc Nephrol. 30:80. PubMed
- Sharma D, et al. 2022. Commun Biol. 5:479. PubMed
- Jiang L, et al. 2022. Front Immunol. 12:730438. PubMed
- Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
- Li P, et al. 2022. EMBO Mol Med. 14:e14511. PubMed
- Hepler C et al. 2018. eLife. 7 pii: e39636. PubMed
- Habisch H, et al. 2008. Cytotherapy. 10:824. PubMed
- Shao M, et al. 2021. Cell Stem Cell. 28(4):685-701.e7. PubMed
- Joffin N, et al. 2021. Cell Stem Cell. 28(4):702-717.e8. PubMed
- Alonso-Herranz L, et al. 2020. Elife. 9:00. PubMed
- Shan B, et al. 2020. Nat Metab. 1332:2. PubMed
- Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
- RRID
- AB_1953270 (BioLegend Cat. No. 136005) AB_1953271 (BioLegend Cat. No. 136006)
- Structure
- Beta chain of the platelet-derived growth factor receptor, a receptor tyrosine kinase that forms homo- or hetero-dimers on the surface after ligand binding.
- Distribution
-
Expressed on embryonic tissues and mesenchymal-derived cells of adult mouse.
- Function
- Play a role in wound healing and act as a chemoattractant for fibroblasts, smooth muscle cells, glial cells, monocytes and neutrophils.
- Ligand/Receptor
- PDGFs
- Cell Type
- Embryonic Stem Cells, Mesenchymal Stem Cells
- Biology Area
- Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers, Stem Cells
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors
- Antigen References
-
1. Soriano P, et al. 1994. Genes Dev. 8:1888
2. Takakura N, et al. 1996. J Invest Dermatol. 107:770
3. Yarden Y, et al. 1986. Nature 323:226
- Gene ID
- 18596 View all products for this Gene ID
- UniProt
- View information about CD140b on UniProt.org
