APC anti-mouse CD140b Antibody
- 产品名称：
- APC anti-mouse CD140b Antibody
- 产品类别：
- 抗体
- 产品编号：
- 136007
- 产品应用：
- 136007
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse PDGFR-β-hIgG1 recombinant fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per 106 cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Additional reported (for the relevant formats) applications include: Western blotting and blocking function2. The LEAF? purified antibody is recommended for functional assays.
- Application References
(PubMed link indicates BioLegend citation) -
- Sano H, et al. 2001. Circulation 103:2955.
- Sano H, et al. 2002. Am. J. Pathol. 161:135. (Block)
- Product Citations
-
- Hepler C et al. 2017. eLife. 6 pii: e27669. PubMed
- Wang W, et al. 2019. Cell Metab. 30:174. PubMed
- Crewe C et al. 2018. Cell. 175(3):695-708 . PubMed
- Kramann R, et al. 2018. JCI Insight. 3. PubMed
- Sakihama H, et al. 2021. Arterioscler Thromb Vasc Biol. :ATVBAHA120315558. PubMed
- Hepler C et al. 2018. eLife. 7 pii: e39636. PubMed
- Alonso-Herranz L, et al. 2020. Elife. 9:00. PubMed
- Ohmori T, et al. 2015. Sci Rep. 5: 15676. PubMed
- Sun X, et al. 2020. eLife. 9:e46756.. PubMed
- Miki K, et al. 2021. Nat Commun. 12:3596. PubMed
- Dahlgren MW et al. 2019. Immunity. 50(3):707-722 . PubMed
- Yu Q, et al. 2016. Cell Res. 10.1038/cr.2016.85. PubMed
- Kumashiro Y, et al. 2015. Small. 6: 681 - 687. PubMed
- Hreha TN, et al. 2020. Physiol Rep. 8:e14401. PubMed
- Krenzlin H, et al. 2019. J Clin Invest. 130:1671. PubMed
- Wong PP, et al. 2020. Cell. 181(6):1346-1363.e21. PubMed
- RRID
- AB_2043971 (BioLegend Cat. No. 136007) AB_2268091 (BioLegend Cat. No. 136008)
- Structure
- Beta chain of the platelet-derived growth factor receptor, a receptor tyrosine kinase that forms homo- or hetero-dimers on the surface after ligand binding.
- Distribution
-
Expressed on embryonic tissues and mesenchymal-derived cells of adult mouse.
- Function
- Play a role in wound healing and act as a chemoattractant for fibroblasts, smooth muscle cells, glial cells, monocytes and neutrophils.
- Ligand/Receptor
- PDGFs
- Cell Type
- Embryonic Stem Cells, Mesenchymal Stem Cells
- Biology Area
- Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers, Stem Cells
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors
- Antigen References
-
1. Soriano P, et al. 1994. Genes Dev. 8:1888
2. Takakura N, et al. 1996. J Invest Dermatol. 107:770
3. Yarden Y, et al. 1986. Nature 323:226
- Gene ID
- 18596 View all products for this Gene ID
- UniProt
- View information about CD140b on UniProt.org
