Purified anti-mouse CD140a Antibody
- 产品名称：
- Purified anti-mouse CD140a Antibody
- 产品类别：
- 抗体
- 产品编号：
- 135901
- 产品应用：
- 135901
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse PDGFR-α-hIgG1 recombinant fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
WB, IHC-P, IHC-F - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported (for relevant formats) applications include: Western Blot, blocking function2, and immunohistochemical staining of paraffin and frozen sections. The LEAF? purified antibody is recommended for functional assays.
- Application References
(PubMed link indicates BioLegend citation) -
- Takakura N, et al. 1996. J. Invest. Dermatol. 107:770.
- Liao C, et al. 2010. J. Clin. Invest. 120:242. (Block)
- Chen H, et al. 2015. ASN Neuro 8:7. PubMed.
- Miyawaki T, et al. 2004. J Neurosci. 24(37): 8124-34. (IHC-F)
- Product Citations
-
- Kim J, et al. 2016. PLoS One. 11: 0158067. PubMed
- Dittmer M, et al. 2018. Mol Brain. 11:25. PubMed
- Weng L, et al. 2016. Sci Rep. 6:38632. PubMed
- Albrecht S, et al. 2016. PLoS One. 11:e0163841. PubMed
- Paulo E, et al. 2018. Sci Rep. 8:11001. PubMed
- Jarjour AA, et al. 2020. Glia. 68(9):1840-1858. PubMed
- Gibson EM, et al. 2019. Cell. 176:43:00. PubMed
- Ghelman J, et al. 2021. Glia. 69(11):2699-2716. PubMed
- Chen H, et al. 2015. ASN Neuro. 8:7. PubMed
- Liu M, et al. 2018. Diabetologia. 61:2333. PubMed
- Shin J, et al. 2018. Diabetes. 67:1068. PubMed
- Yin W, et al. 2022. Development. 149:. PubMed
- Yoshioka K, et al. 2020. Front Cell Dev Biol. 0.884027778. PubMed
- Iida Y, et al. 2020. J Immunother Cancer. 8:. PubMed
- Maller O, et al. 2020. Nat Mater. 20:548. PubMed
- RRID
- AB_1953327 (BioLegend Cat. No. 135901) AB_1953328 (BioLegend Cat. No. 135902)
- Structure
- Alpha chain of the platelet-derived growth factor receptor, a receptor tyrosine kinase that forms homo- or hetero-dimers on the surface after ligand binding.
- Distribution
-
Expressed on embryonic tissues and mesenchymal-derived cells of adult mouse.
- Function
- Play a role in wound healing and act as a chemoattractant for fibroblasts, smooth muscle cells, glial cells, monocytes and neutrophils.
- Ligand/Receptor
- PDGFs
- Cell Type
- Embryonic Stem Cells, Mesenchymal cells, Mesenchymal Stem Cells
- Biology Area
- Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers, Stem Cells
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors
- Antigen References
-
1. Mukouyama YS, et al. 2006. Proc Natl Acad Sci USA. 103(5):1551
2. Miyawaki T, et al. 2004. J Neurosci. 24(37):8124
3. Takakura N, et al. 1997. J Histochem Cytochem. 45(6):883
- Gene ID
- 18595 View all products for this Gene ID
- UniProt
- View information about CD140a on UniProt.org
