Purified anti-SARS-CoV-2 S Protein S1 Recombinant
- 产品名称:
- Purified anti-SARS-CoV-2 S Protein S1 Recombinant
- 产品类别:
- 抗体
- 产品编号:
- 940801
- 产品应用:
- 940801
- Verified Reactivity
- SARS-CoV-2
- Antibody Type
- Recombinant
- Host Species
- Human
- Formulation
- 140 mM Hepes, pH 7.5, 70 mM NaCl, 32 mM NaOAc, 0.035% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 1.0 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Prior to use, quick spin the antibody vial to ensure recovery of maximum volume. Antibody can be stored in single use aliquots in -20°C for 2 years. Avoid repeated freeze and thaws.
- Application
-
Block?- Quality tested
ELISA - Verified
- Recommended Usage
Each lot is quality control tested by its ability to block the binding between recombinant human ACE2 (Cat. No. 792002) and recombinant SARS-CoV-2 S Protein S1-Fc chimera (Cat. No. 793004). ND50 range is 0.4 - 4 μg/mL.?Recommended usage concentration for direct ELISA application is 27.7 ng/mL. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Clone name AM043105 is also referred to as clone 105-43.
- Application References
(PubMed link indicates BioLegend citation) -
1. Wan J. et al. 2020. Cell Rep. 32(3):107918?
- RRID
- AB_2888750 (BioLegend Cat. No. 940801) AB_2888750 (BioLegend Cat. No. 940802)
- Structure
- Spike glycoprotein is a homotrimer. Each monomer consists of 1,273 a.a with a molecular weight of approximately 141 kD and consists of S1 and S2 subunits. S1 subunit is 673 a.a. long.
- Distribution
-
Viral envelope protein, host cell membrane, host cell endoplasmic reticulum-Golgi intermediate compartment membrane
- Function
- Host cell surface receptor binding
- Interaction
- ACE2
- Ligand/Receptor
- ACE2
- Biology Area
- COVID-19
- Antigen References
-
1. Walls A.C. et al.2020. Cell 181(2):281-292
2. Yan R. et al. 2020 Science 367 (6485):1444-1448
3. Wrapp D. et al.2020 Science 367 (6483):1260-126
4. Shang J.et al.2020 PNAS 117(21):11727-11734
- Gene ID
- 43740568 View all products for this Gene ID
- UniProt
- View information about Viral Protein on UniProt.org