Purified anti-SARS-CoV-2 S Protein S1 Recombinant
- 产品名称：
- Purified anti-SARS-CoV-2 S Protein S1 Recombinant
- 产品类别：
- 抗体
- 产品编号：
- 938501
- 产品应用：
- 938501
- Verified Reactivity
- SARS-CoV-2
- Antibody Type
- Recombinant
- Host Species
- Human
- Immunogen
- SARS-CoV-2
- Formulation
- 140 mM Hepes, pH 7.5, 70 mM NaCl, 32 mM NaOAc, 0.035% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 1.0 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
Block - Quality tested
ELISA - Verified
- Recommended Usage
Each lot is quality control tested by its ability to block the binding between recombinant human ACE2 (Cat. No. 792002) and SARS-CoV-2 S protein S1-Fc chimera (Cat. No. 793004). ND50 range is 0.1?- 1.0?μg/mL. It is recommended that the reagent be titrated for optimal performance for each application.
Recommended concentration for direct ELISA application is 45 ng/mL.
- Application Notes
Note: Clone AM009105 is also referred to as Clone 105-9.
- Additional Product Notes
Prior to use, quick spin the antibody vial to ensure recovery of maximum volume.
Antibody can be stored in single use aliquots in -20°C for 2 years. Avoid repeated freeze and thaws.
- Application References
(PubMed link indicates BioLegend citation) -
- Wan J, et al. 2020. bioRxiv. doi: https://doi.org/10.1101/2020.05.19.104117
- Product Citations
-
- Alves J, et al. 2021. Sci Rep. 11:18428. PubMed
- RRID
- AB_2876762 (BioLegend Cat. No. 938501) AB_2876762 (BioLegend Cat. No. 938502)
- Structure
- Spike glycoprotein is a homotrimer. Each monomer consists of 1,273 a.a. with a molecular weight of approximately 141 kD and consists of S1 and S2. S1 subunit is 673 a.a. long.
- Distribution
-
Viral envelope protein, host cell membrane, host cell endoplasmic reticulum-Golgi intermediate compartment membrane
- Function
- Host cell surface receptor binding
- Interaction
- ACE2
- Ligand/Receptor
- ACE2
- Biology Area
- COVID-19
- Antigen References
-
- Walls AC, et al. 2020. Cell. 181(2):281-292.
- Yan R, et al. 2020. Science. 367 (6485):1444-1448.
- Wrapp D, et al. 2020. Science. 367 (6483):1260-1263.
- Shang J, et al. 2020. PNAS. 117(21):11727-11734
- Gene ID
- 43740568 View all products for this Gene ID
- UniProt
- View information about Viral Protein on UniProt.org
