Purified anti-SARS-CoV-2 S Protein S1 Recombinant -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 2052	1

规格

价格

库存

25µg

￥ 2052

Product Details

Verified Reactivity: SARS-CoV-2
Antibody Type: Recombinant
Host Species: Human
Immunogen: SARS-CoV-2
Formulation: 140mM Hepes, pH 7.5, 70 mM NaCl,, 32 mM NaOAc, 0.035% sodium azide
Preparation: The antibody was purified by affinity chromatography.
Concentration: 1.0 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: Block?- Quality tested
ELISA -?Verified
Recommended Usage: Each lot is quality control tested by its ability to block the binding between recombinant human ACE2 (Cat. No. 792002) and SARS-CoV-2 S protein S1-Fc chimera (Cat. No. 793004). ND₅₀ range is 0.03 - 0.12 μg/mL. It is recommended that the reagent be titrated for optimal performance for each application.

Recommended concentration for direct ELISA application is 45 ng/mL.
Application Notes: Note: Clone AM001414 is also referred to as Clone 414-1
Additional Product Notes: Prior to use, quick spin the antibody vial to ensure recovery of maximum volume.

Antibody can be stored in single use aliquots in -20°C for 2 years. Avoid repeated freeze and thaws.
Application References (PubMed link indicates BioLegend citation): Wan J. et al. 2020. bioRxiv. doi: https://doi.org/10.1101/2020.05.19.104117
RRID: AB_2876764 (BioLegend Cat. No. 938701) AB_2876764 (BioLegend Cat. No. 938702)

Antigen Details

Structure

Spike glycoprotein is a homotrimer. Each monomer consists of 1,273 a.a with a molecular weight of approximately 141 kD and consists of S1 and S2 subunits. S1 subunit is 673 a.a. long.

Distribution

Viral envelope protein, host cell membrane, host cell endoplasmic reticulum-Golgi intermediate compartment membrane

Function

Host cell surface receptor binding

Interaction

ACE2

Ligand/Receptor

ACE2

Biology Area

COVID-19

Antigen References

Walls AC, et al. 2020. Cell. 181(2):281-292.
Yan R, et al. 2020. Science. 367 (6485):1444-1448.
Wrapp D, et al. 2020. Science. 367 (6483):1260-1263.
Shang J, et al. 2020. PNAS. 117(21):11727-11734

Gene ID

43740568 View all products for this Gene ID

UniProt

View information about Viral Protein on UniProt.org

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