PE anti-human CD62P (P-Selectin) Antibody
- 产品名称：
- PE anti-human CD62P (P-Selectin) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 304905
- 产品应用：
- 304905
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1284 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- Chimpanzee
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections4 and in vitro blocking of adhesion of platelets1. The Ultra-LEAF? purified antibody (Endotoxin < 0.01 EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for functional assays (Cat. No. 304947 & 304948).
- Application References
(PubMed link indicates BioLegend citation) -
- Skinner M, et al. 1991. J. Biol. Chem. 266:5371. (Block)
- Kishimoto T, et al. Eds. 1997. Leucocyte Typing VI. Garland Publishing Inc. London.
- Yen YT, et al. 2006. J. Virol. 80:2684.
- Sato Y, et al. 2005. Blood 106:428. (IHC)
- Product Citations
-
- Buijsers B, et al. 2022. Front Immunol. 12:759570. PubMed
- Garcia-Larragoiti N, et al. 2021. J Thromb Haemost. 19:2572. PubMed
- Machata S, et al. 2021. Front Immunol. 11:565869. PubMed
- Slingsby MHL, et al. 2021. Haematologica. Online ahead of print. PubMed
- Artemenko E, et al. 2016. Biochem J. 473: 435 - 448. PubMed
- Best MG et al. 2017. Cancer cell. 32(2):238-252 . PubMed
- Petersen-Uribe ?, et al. 2021. Int J Mol Sci. 22:. PubMed
- Sung PS, et al. 2019. Nat Commun. 10:2402. PubMed
- Ye Z, et al. 2019. Mediators Inflamm. 2019:8709583. PubMed
- Zhang S, et al. 2012. PLoS One. 7:e40641. PubMed
- Bennett JA, et al. 2020. Nat Commun. 2.874305556. PubMed
- Lee S, et al. 2021. Nature. 599:283. PubMed
- Crooks M, et al. 2014. PLoS One. 9:111347. PubMed
- Welsh J, et al. 2011. Br J Haematol. 154:122. PubMed
- Marsden AJ, et al. 2021. ACS Pharmacol Transl Sci. 4:1567. PubMed
- Deng W, et al. 2016. Nat Commun. 7: 12863. PubMed
- Han P, et al. 2020. Sci Adv. 6:eaaz1580. PubMed
- Karampini E, et al. 2019. Haematologica. 104:2091. PubMed
- RRID
- AB_314477 (BioLegend Cat. No. 304905) AB_314478 (BioLegend Cat. No. 304906)
- Structure
- Selectin, type I glycoprotein, 140 kD
- Distribution
-
Activated platelets, megakaryocytes, endothelial cells
- Function
- Adhesion, neutrophil rolling, platelet-neutrophil and platelet-monocyte interactions
- Ligand/Receptor
- CD162 (PSGL-1), CD24 and sialylated Lewis X
- Cell Type
- Endothelial cells, Megakaryocytes, Neutrophils, Platelets
- Biology Area
- Cell Adhesion, Cell Biology, Immunology, Neuroscience, Synaptic Biology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. McEver R, et al. 1995. J. Biol. Chem. 270:11025.
2. Varki A. 1994. P. Natl. Acad. Sci. USA 91:7390.
- Gene ID
- 6403 View all products for this Gene ID
- UniProt
- View information about CD62P on UniProt.org
