Alexa Fluor® 647 anti-human CD62P (P-Selectin)
- 产品名称：
- Alexa Fluor® 647 anti-human CD62P (P-Selectin)
- 产品类别：
- 抗体
- 产品编号：
- 304918
- 产品应用：
- 304918
[价格]
| 规格 |
价格 |
库存 |
| 100tests |
￥ 3180 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- Chimpanzee
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 647 under optimal conditions.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
* Alexa Fluor? 647 has a maximum emission of 668 nm when it is excited at 633nm / 635nm.
Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.
View full statement regarding label licenses - Excitation Laser
- Red Laser (633 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections4 and in vitro blocking of adhesion of platelets1. The Ultra-LEAF? purified antibody (Endotoxin < 0.01 EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for functional assays (Cat. No. 304947 & 304948).
- Application References
(PubMed link indicates BioLegend citation) -
- Skinner M, et al. 1991. J. Biol. Chem. 266:5371. (Block)
- Kishimoto T, et al. Eds. 1997. Leucocyte Typing VI. Garland Publishing Inc. London.
- Yen YT, et al. 2006. J. Virol. 80:2684.
- Sato Y, et al. 2005. Blood 106:428. (IHC)
- Product Citations
-
- Loelius SG et al. 2018. Current protocols in toxicology. 76(1):e46 . PubMed
- Cruz MA, et al. 2022. Nat Nanotechnol. 17:1004. PubMed
- Modery-Pawlowski C, et al. 2013. Biomaterials. 34:3031. PubMed
- Verheul H, et al. 2007. Clin Cancer Res. 4.250694444. PubMed
- Huang J, et al. 2022. Int J Mol Sci. 23:. PubMed
- Jooss NJ, et al. 2019. Int J Mol Sci. 20. PubMed
- Jahn K, et al. 2020. Blood Adv. 4:6315. PubMed
- Fernández DI, et al. 2022. iScience. 25:103718. PubMed
- Hrdinova J, et al. 2022. Int J Mol Sci. 23:. PubMed
- Sachs L, et al. 2022. Commun Biol. 5:86. PubMed
- Han P, et al. 2020. Sci Adv. 6:eaaz1580. PubMed
- RRID
- AB_2185110 (BioLegend Cat. No. 304918)
- Structure
- Selectin, type I glycoprotein, 140 kD
- Distribution
-
Activated platelets, megakaryocytes, endothelial cells
- Function
- Adhesion, neutrophil rolling, platelet-neutrophil and platelet-monocyte interactions
- Ligand/Receptor
- CD162 (PSGL-1), CD24 and sialylated Lewis X
- Cell Type
- Endothelial cells, Megakaryocytes, Neutrophils, Platelets
- Biology Area
- Cell Adhesion, Cell Biology, Immunology, Neuroscience, Synaptic Biology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. McEver R, et al. 1995. J. Biol. Chem. 270:11025.
2. Varki A. 1994. P. Natl. Acad. Sci. USA 91:7390.
- Gene ID
- 6403 View all products for this Gene ID
- UniProt
- View information about CD62P on UniProt.org
