上海细胞库
人源细胞系| 稳转细胞系| 基因敲除株| 基因点突变细胞株| 基因过表达细胞株| 重组细胞系| 猪的细胞系| 马细胞系| 兔的细胞系| 犬的细胞系| 山羊的细胞系| 鱼的细胞系| 猴的细胞系| 仓鼠的细胞系| 狗的细胞系| 牛的细胞| 大鼠细胞系| 小鼠细胞系| 其他细胞系|
人源细胞系| 稳转细胞系| 基因敲除株| 基因点突变细胞株| 基因过表达细胞株| 重组细胞系| 猪的细胞系| 马细胞系| 兔的细胞系| 犬的细胞系| 山羊的细胞系| 鱼的细胞系| 猴的细胞系| 仓鼠的细胞系| 狗的细胞系| 牛的细胞| 大鼠细胞系| 小鼠细胞系| 其他细胞系|
| 规格 | 价格 | 库存 |
|---|---|---|
| 50µg | ￥ 996 | 1 |
WB - Quality tested
Block, ELISA, IP, IHC-F - Reported in the literature, not verified in house
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
Additional reported applications (for the relevant formats) include: ELISA1,2, immunoprecipitation1and Western blot1,2 from cell lysates, immunohistochemical staining1, 3 of frozen and paraffin embedded tissue sections and in whole-mount mouse embryos, in vivo blocking1, 5 of VEGF-C binding to inhibit angiogenesis, lymphangiogenesis, growth and metastasis of different tumor cells, in vitro blocking4 of VEGF-C binding to induce dispersion of endothelial cell clusters.
This clone detect multiple bands by western blot: a ~140 kD band corresponding to cleaved/soluble VEGFR-3, and 220 and 230 kD bands corresponding to unglycosylated and glycosylated full length VEGFR-3 (Bando, et al. 2004. Int J Canc. 111:184.)
This product has been reported by a collaborator to work for immunohistochemical staining of frozen tissue sections.
Expressed on vascular endothelial cells during fetal development, constitutively expressed on lymphatic endothelium in adult mice, induced in tumors with active angiogenesis.
1. Uhrin P, et al. 2010. Blood 115:3997.
2. Wang Y, et al. 2010. Nature 465:483.
3. Akobsson L, et al. 2009. Biochem. Soc. T. 37:1233.
4. Tammela T, et al. 2010. Nature 454:656.
5. Huang G and Chen L. 2008. Cancer Biother. Radio. 23:661.
6. Zhang YJ and Fang JY. 2008. J. Gastroen. Hepatol. 23:856.
