FITC anti-human CD73 (Ecto-5'-nucleotidase) A
- 产品名称：
- FITC anti-human CD73 (Ecto-5'-nucleotidase) A
- 产品类别：
- 抗体
- 产品编号：
- 344015
- 产品应用：
- 344015
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1344 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
- Application Notes
Additional reported applications (for the relevant formats) include:immunofluorescence3.
Clone AD2 has been noted to induce clustering and internalization of CD73 in vivo and inhibit metastasis in a murine breast cancer xenograft model4.
- Application References
(PubMed link indicates BioLegend citation) -
- Nakamura T, et al. 1993. J. Immunol. 151:6933.
- Liao J, et al. 2011. J Endod. 37:1217. PubMed
- Touboul C, et al. 2013. J. Transl. Med. 11:28. (IF)
- Terp MG, et al. 2013. J Immunol. 191: 4165-73 (Block)
- Product Citations
-
- Yusa K, et al. 2016. Sci Rep. 6:29462. PubMed
- Goodnough LH, et al. 2020. JBMR Plus. 4:e10398. PubMed
- Liu X, et al. 2020. Exp Ther Med. 1.258333333. PubMed
- Tu S, et al. 2020. Cellular Signalling. 73:109695. PubMed
- Vishnoi M, et al. 2018. Cancer Res. 78:5349. PubMed
- Han J, et al. 2022. FEBS J. 289:417. PubMed
- Yerneni SS, et al. 2021. MBio. 12:e0165721. PubMed
- Morad G, et al. 2020. International Journal of Molecular Sciences. 21(11):3851. PubMed
- Sun W, et al. 2019. Exp Ther Med. 17:2199. PubMed
- Liu Y, et al. 2022. iScience. 25:104405. PubMed
- Yan K, et al. 2022. iScience. 25:104822. PubMed
- Gao P, et al. 2017. Cytotechnology. 69:751. PubMed
- Yu C, et al. 2020. Sci Rep. 10:14521. PubMed
- Ambrosi TH, et al. 2020. Aging Cell. 19:e13164. PubMed
- Ayhan S, et al. 2021. Journal of Cell Science. 134(6):. PubMed
- Zhang Q, et al. 2021. Bone Joint Res. 10:226. PubMed
- Keshtkar S, et al. 2021. Stem Cells Int. 8857457:2020. PubMed
- Ludwig N, et al. 2020. Angiogenesis. 1.374305556. PubMed
- Aomatsu E, et al. 2014. Sci Rep. 4:3652. PubMed
- He Z, et al. 2020. J Exp Clin Cancer Res. 39:140. PubMed
- Fei D, et al. 2021. Front Cell Dev Biol. 9:687258. PubMed
- Pauken CM, et al. 2021. Cancers (Basel). 13:. PubMed
- Festag J, et al. 2020. Mol Ther Nucleic Acids. 1.330555556. PubMed
- Vishnoi M, et al. 2019. Mol Oncol. 13(9): 1913. PubMed
- Boucher JM, et al. 2018. Cardiovasc Drugs Ther. 32:519. PubMed
- Zheng C, et al. 2021. J Extracell Vesicles. 10:e12109. PubMed
- Sprouse ML, et al. 2019. Int J Mol Sci. 20:8. PubMed
- RRID
- AB_2561808 (BioLegend Cat. No. 344015) AB_2561809 (BioLegend Cat. No. 344016)
- Structure
- GPI-linked 5'-nucleotidase, 70 kD
- Distribution
-
Subsets of T cells and B cells, mesenchymal stem cells, follicular dendritic cells, endothelial cells, and epithelial cells
- Function
- Catalyses dephosphorylation of adenosine monophosphate, costimulates T cell activation, mediates adhesion of lymphocytes to follicular dendritic cells and endothelial cells
- Cell Type
- B cells, Dendritic cells, Endothelial cells, Epithelial cells, Mesenchymal Stem Cells, T cells, Tregs
- Biology Area
- Costimulatory Molecules, Immunology, Stem Cells
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Zola H, et al. 2007. Leukocyte and stromal Cell Molecules:the CD Markers. A John Wiley & Sons Inc, Publication.
2. Airas L and Jalkanen? S, et al. 1996. Blood 88:1755.
3. Gutensohn W, et al. 1995. Cell Immunol. 161:213.
4. Airas L, et al. 1995. J. Exp. Med. 182:1603.
- Gene ID
- 4907 View all products for this Gene ID
- UniProt
- View information about CD73 on UniProt.org
