APC anti-human CD73 (Ecto-5'-nucleotidase) An
- 产品名称：
- APC anti-human CD73 (Ecto-5'-nucleotidase) An
- 产品类别：
- 抗体
- 产品编号：
- 344005
- 产品应用：
- 344005
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1992 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Additional reported applications (for the relevant formats) include:immunofluorescence3.
Clone AD2 has been noted to induce clustering and internalization of CD73 in vivo and inhibit metastasis in a murine breast cancer xenograft model4.
- Application References
(PubMed link indicates BioLegend citation) -
- Nakamura T, et al. 1993. J. Immunol. 151:6933.
- Liao J, et al. 2011. J Endod. 37:1217. PubMed
- Touboul C, et al. 2013. J. Transl. Med. 11:28. (IF)
- Terp MG, et al. 2013. J Immunol. 191: 4165-73 (Block)
- Product Citations
-
- Ragni E, et al. 2021. Cells. 10: . PubMed
- Guney-Esken G, et al. 2021. Stem Cell Res Ther. 12:287. PubMed
- Jeon SB, et al. 2022. Int J Stem Cells. Online ahead of print. PubMed
- Kokkinopoulos I, et al. 2021. Sci Rep. 11:15759. PubMed
- Morton JJ, et al. 2018. Mol Carcinog. 57:1651. PubMed
- Ragni E, et al. 2022. Biomolecules. 12:. PubMed
- Chulpanova DS, et al. 2020. Bioengineering (Basel). 7:00. PubMed
- Le X, et al. 2021. J Thorac Oncol. 16:583. PubMed
- Santos J, et al. 2013. J Transl Med. 11:18. PubMed
- Xu H, et al. 2022. Cell Death Dis. 13:478. PubMed
- Li J, et al. 2021. Mol Med Rep. 1:23. PubMed
- Wang D, et al. 2020. J Cell Mol Med. 24:4212. PubMed
- Hopf A, et al. 2022. Bioengineering (Basel). 9:. PubMed
- Bruveris FF, et al. 2020. Development. 147:00:00. PubMed
- Nazari-Shafti TZ, et al. 2020. Biomolecules. 10:00. PubMed
- Bordin A, et al. 2019. Stem Cells Int. 2019:1516746. PubMed
- Uslu M, et al. 2020. J Cell Physiol. 235:9644. PubMed
- Moreno-Fernandez M, et al. 2011. Blood. 117:5372. PubMed
- Chulpanova DS, et al. 2021. Biology (Basel). 10:. PubMed
- Guney-Esken G, et al. 2021. Methods Mol Biol. 2549:23. PubMed
- Hofmann L, et al. 2022. Front Med (Lausanne). 9:904295. PubMed
- Buschmann J, et al. 2013. Cytotherapy. 15:1098. PubMed
- Xu L, et al. 2022. Int J Mol Sci. 23:. PubMed
- Ran Y, et al. 2022. Stem Cell Res Ther. 13:507. PubMed
- Siciliano C, et al. 2016. Stem Cell Res. 17: 342-351. PubMed
- Safi R, et al. 2021. Photodermatol Photoimmunol Photomed. 37:202. PubMed
- Papait A, et al. 2022. Front Immunol. 13:960909. PubMed
- Deng P, et al. 2020. Bone Res. 8:39. PubMed
- RRID
- AB_1877158 (BioLegend Cat. No. 344005) AB_1877157 (BioLegend Cat. No. 344006)
- Structure
- GPI-linked 5'-nucleotidase, 70 kD
- Distribution
-
Subsets of T cells and B cells, mesenchymal stem cells, follicular dendritic cells, endothelial cells, and epithelial cells
- Function
- Catalyses dephosphorylation of adenosine monophosphate, costimulates T cell activation, mediates adhesion of lymphocytes to follicular dendritic cells and endothelial cells
- Cell Type
- B cells, Dendritic cells, Endothelial cells, Epithelial cells, Mesenchymal Stem Cells, T cells, Tregs
- Biology Area
- Costimulatory Molecules, Immunology, Stem Cells
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Zola H, et al. 2007. Leukocyte and stromal Cell Molecules:the CD Markers. A John Wiley & Sons Inc, Publication.
2. Airas L and Jalkanen? S, et al. 1996. Blood 88:1755.
3. Gutensohn W, et al. 1995. Cell Immunol. 161:213.
4. Airas L, et al. 1995. J. Exp. Med. 182:1603.
- Gene ID
- 4907 View all products for this Gene ID
- UniProt
- View information about CD73 on UniProt.org
