Purified anti-mouse CD285 (TLR5) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 3180	1

规格

价格

库存

100µg

￥ 3180

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

TLR5-transfected Ba/F3 cells

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C.

Application

FC - Quality tested
IP - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications for the relevant formats include: immunoprecipitation of TLR5 from cell lysates^1,2.

Application References (PubMed link indicates BioLegend citation)

Shibata T, et al. Int Immunol. 24:613. (IP, FC)
Huh JW, et al. 2014. Proc. Natl. Acad. Sci. USA. 111:7072. (IP)

Product Citations

Pushalkar S, et al. 2018. Cancer Discov. 0.613194444. PubMed

RRID

AB_2563693 (BioLegend Cat. No. 148102)

Antigen Details

Structure: Type 1 transmembrane protein, 98 kD
Distribution: Neutrophils, CD11b, Ly6C, classical monocytes, dendritic cells, mucosal epithelium
Interaction: Interacts with MyD88 and TRAF6 leading to NF-κB activation and production of cytokines.
Ligand/Receptor: Flagellin
Cell Type: Dendritic cells, Monocytes, Neutrophils
Biology Area: Immunology, Innate Immunity
Molecular Family: CD Molecules
Antigen References: 1. López-Yglesias AH, et al. 2014. J. Immunol. 192:1587.?
2. Burdelya L, et al. 2013. Proc. Natl. Acad. Sci. USA. 110:E1857.?
3. Carapau D, et al. 2013. Infect. Immun. 81:4350.?
4. Kinnebrew M, et al. 2012. Immunity. 36:276.?
5. Sebastiani G, et al. 2000. Genomics. 64:230.
Gene ID: 53791 View all products for this Gene ID
UniProt: View information about CD285 on UniProt.org

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