PerCP/Cyanine5.5 anti-mouse CD93 (AA4.1, early B l
- 产品名称：
- PerCP/Cyanine5.5 anti-mouse CD93 (AA4.1, early B l
- 产品类别：
- 抗体
- 产品编号：
- 136511
- 产品应用：
- 136511
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Pre-B lymphoma 70Z/3
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.
- Additional Product Notes
- BioLegend is in the process of converting the name PerCP/Cy5.5 to PerCP/Cyanine5.5. The dye molecule remains the same, so you should expect the same quality and performance from our PerCP/Cyanine5.5 products. Contact Technical Service if you have any questions.
- Application References
(PubMed link indicates BioLegend citation) -
- McKearn JP, et al. 1984. J. Immunol. 132:332
- Hanihara-Tatsuzaawa F, et al. 2014. J Biol Chem. 289:30925. PubMed
- Product Citations
-
- Schloss MJ, et al. 2022. Nat Immunol. 23:605. PubMed
- Philpott J, et al. 2022. Immunohorizons. 6:366. PubMed
- Avery DT, et al. 2018. J Exp Med. 215:2073. PubMed
- Khiew SH, et al. 2020. J Clin Invest. 130:3453. PubMed
- Simoni L, et al. 2020. Cell Rep. 33:108330. PubMed
- Kunishita Y, et al. 2020. Front Immunol. 11:98. PubMed
- RRID
- AB_10645333 (BioLegend Cat. No. 136511) AB_10642683 (BioLegend Cat. No. 136512)
- Structure
- A 130-140 kD C-type lectin like type I transmembrane protein, also known as complement component 1, q subcomponent (C1qR1), C1qRp collectin receptor (C1qRp), or AA4 antigen.
- Distribution
- Expressed during immature B lymphocytes, hematopoietic progenitors and stem cells in bone marrow, immature dendritic cells, monocytes, macrophages, and endothelial cells.
- Function
- CD93 plays an important role in maintaining of plasma cells in bone marrow niches. It may play a role in uptake of particles by DC and the in vivo clearance of dying cells by macrophages.
- Cell Type
- B cells, Dendritic cells, Endothelial cells, Hematopoietic stem and progenitors, Macrophages, Monocytes
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
- Molecular Family
- CD Molecules
- Antigen References
-
1. Steinberger P, et al. 2002. J. Leukoc. Biol. 71:133
2. Chevrier S, et al. 2009. Proc. Nat. Acad. Sci. U. S. A. 106:3895
3. Norsworthy PJ, et al. 2004. J. Immunol. 172:3406
4. Li YS, et al. 1996. Immunity 5:527
5. Szilvassy SJ, et al. 1993. Blood 81:2310
- Gene ID
- 17064 View all products for this Gene ID
- UniProt
- View information about CD93 on UniProt.org
