PE/Cyanine7 anti-mouse CD93 (AA4.1, early B lineag
- 产品名称：
- PE/Cyanine7 anti-mouse CD93 (AA4.1, early B lineag
- 产品类别：
- 抗体
- 产品编号：
- 136505
- 产品应用：
- 136505
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Pre-B lymphoma 70Z/3
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
- Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Additional Product Notes
- BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
- Application References
(PubMed link indicates BioLegend citation) -
- McKearn JP, et al. 1984. J. Immunol. 132:332
- Hanihara-Tatsuzaawa F, et al. 2014. J Biol Chem. 289:30925. PubMed
- Product Citations
-
- Barrett N, et al. 2016. Cell Rep. 16: 1039-1054. PubMed
- Huang J, et al. 2021. Immunity. 54(4):673-686.e4. PubMed
- Delgado-Benito V, et al. 2020. J Exp Med. 217:00:00. PubMed
- Geng T, et al. 2022. Methods Mol Biol. 2585:71. PubMed
- Barajas‐Mora EM et al. 2018. Molecular cell. 73(1):48-60 . PubMed
- Lam WY et al. 2018. Cell reports. 24(9):2479-2492 . PubMed
- Li H, et al. 2020. Nature. 584:274. PubMed
- Noviski M, et al. 2018. Elife. 7:e35074. PubMed
- Jacoby E, et al. 2016. Nat Commun. 7:12320. PubMed
- Colliou N, et al. 2015. Toxins. 7: 3805 - 3817. PubMed
- Lehrke MJ, et al. 2021. Elife. 10:. PubMed
- Kobia FM, et al. 2020. PLoS Biol. 18:e3000850. PubMed
- Wright JA, et al. 2021. Front Immunol. 12:705307. PubMed
- Yamada H, et al. 2018. J Immunol. 201:3492. PubMed
- Zhang B, et al. 2021. Nature. 599:471. PubMed
- Rossi G, et al. 2022. Sci Rep. 12:13380. PubMed
- RRID
- AB_2044011 (BioLegend Cat. No. 136505) AB_2044012 (BioLegend Cat. No. 136506)
- Structure
- A 130-140 kD C-type lectin like type I transmembrane protein, also known as complement component 1, q subcomponent (C1qR1), C1qRp collectin receptor (C1qRp), or AA4 antigen.
- Distribution
- Expressed during immature B lymphocytes, hematopoietic progenitors and stem cells in bone marrow, immature dendritic cells, monocytes, macrophages, and endothelial cells.
- Function
- CD93 plays an important role in maintaining of plasma cells in bone marrow niches. It may play a role in uptake of particles by DC and the in vivo clearance of dying cells by macrophages.
- Cell Type
- B cells, Dendritic cells, Endothelial cells, Hematopoietic stem and progenitors, Macrophages, Monocytes
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
- Molecular Family
- CD Molecules
- Antigen References
-
1. Steinberger P, et al. 2002. J. Leukoc. Biol. 71:133
2. Chevrier S, et al. 2009. Proc. Nat. Acad. Sci. U. S. A. 106:3895
3. Norsworthy PJ, et al. 2004. J. Immunol. 172:3406
4. Li YS, et al. 1996. Immunity 5:527
5. Szilvassy SJ, et al. 1993. Blood 81:2310
- Gene ID
- 17064 View all products for this Gene ID
- UniProt
- View information about CD93 on UniProt.org
