FITC anti-mouse CD93 (AA4.1, early B lineage) Anti
- 产品名称：
- FITC anti-mouse CD93 (AA4.1, early B lineage) Anti
- 产品类别：
- 抗体
- 产品编号：
- 136507
- 产品应用：
- 136507
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Pre-B lymphoma 70Z/3
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- McKearn JP, et al. 1984. J. Immunol. 132:332
- Hanihara-Tatsuzaawa F, et al. 2014. J Biol Chem. 289:30925. PubMed
- Product Citations
-
- Hutter K, et al. 2022. Front Immunol. 13:967914. PubMed
- Paiva RS, et al. 2021. Eur J Immunol. 51:1968. PubMed
- Hutter K, et al. 2020. FEBS J. . PubMed
- Schoeler K, et al. 2019. FEBS J. 10.1111/febs.14934. PubMed
- Wang W, et al. 2021. J Am Heart Assoc. 10:e019142. PubMed
- Yin S et al. 2019. Cancer cell. 35(2):283-296 . PubMed
- RRID
- AB_10570499 (BioLegend Cat. No. 136507) AB_2076152 (BioLegend Cat. No. 136508)
- Structure
- A 130-140 kD C-type lectin like type I transmembrane protein, also known as complement component 1, q subcomponent (C1qR1), C1qRp collectin receptor (C1qRp), or AA4 antigen.
- Distribution
- Expressed during immature B lymphocytes, hematopoietic progenitors and stem cells in bone marrow, immature dendritic cells, monocytes, macrophages, and endothelial cells.
- Function
- CD93 plays an important role in maintaining of plasma cells in bone marrow niches. It may play a role in uptake of particles by DC and the in vivo clearance of dying cells by macrophages.
- Cell Type
- B cells, Dendritic cells, Endothelial cells, Hematopoietic stem and progenitors, Macrophages, Monocytes
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
- Molecular Family
- CD Molecules
- Antigen References
-
1. Steinberger P, et al. 2002. J. Leukoc. Biol. 71:133
2. Chevrier S, et al. 2009. Proc. Nat. Acad. Sci. U. S. A. 106:3895
3. Norsworthy PJ, et al. 2004. J. Immunol. 172:3406
4. Li YS, et al. 1996. Immunity 5:527
5. Szilvassy SJ, et al. 1993. Blood 81:2310
- Gene ID
- 17064 View all products for this Gene ID
- UniProt
- View information about CD93 on UniProt.org
