APC anti-mouse CD93 (AA4.1, early B lineage) Antib
- 产品名称：
- APC anti-mouse CD93 (AA4.1, early B lineage) Antib
- 产品类别：
- 抗体
- 产品编号：
- 136509
- 产品应用：
- 136509
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Pre-B lymphoma 70Z/3
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- McKearn JP, et al. 1984. J. Immunol. 132:332
- Hanihara-Tatsuzaawa F, et al. 2014. J Biol Chem. 289:30925. PubMed
- Product Citations
-
- Takano J, et al. 2022. Nat Commun. 13:7159. PubMed
- Wenzek C, et al. 2022. iScience. 25:105540. PubMed
- Chappaz S, et al. 2021. Cell Reports. 36(3):109430. PubMed
- Kaku H, et al. 2014. J Immunol. 193:5904. PubMed
- Pessoa Rodrigues C, et al. 2021. Sci Adv. 7:. PubMed
- Riether C, et al. 2021. Cell Reports. 34(4):108663. PubMed
- Fistonich C, et al. 2018. J Exp Med. 215:2586. PubMed
- Benhamou D, et al. 2018. Front Immunol. 2.260416667. PubMed
- Pawaria S, et al. 2020. Arthritis Rheumatol. 72:359. PubMed
- Jia W, et al. 2021. Nat Commun. 12:2118. PubMed
- Kobayashi M, et al. 2020. Bio Protoc. 10:e3601. PubMed
- Uslu K, et al. 2014. J Immunol. 192:3582. PubMed
- Hutter K, et al. 2020. FEBS J. . PubMed
- Schoeler K, et al. 2019. FEBS J. 10.1111/febs.14934. PubMed
- Chen RJ, et al. 2022. iScience. 25:105595. PubMed
- Lazarian G, et al. 2021. Cancer Cell. 39(3):380-393.e8. PubMed
- Muri J, et al. 2020. Cell Reports. 29(9):2731-2744.e4.. PubMed
- Ghezraoui H, et al. 2018. Nature. 560:122. PubMed
- Walker JS, et al. 2021. Nat Commun. 12:6338. PubMed
- Fiala G, et al. 2015. J Exp Med. 212: 1693-1708. PubMed
- Andrés B, et al. 2012. J Immunol. 189:2300. PubMed
- Roberto MP, et al. 2021. Immunity. 54(8):1807-1824.e14. PubMed
- Li Z et al. 2018. Immunity. 49(4):640-653 . PubMed
- RRID
- AB_2275879 (BioLegend Cat. No. 136509) AB_2275868 (BioLegend Cat. No. 136510)
- Structure
- A 130-140 kD C-type lectin like type I transmembrane protein, also known as complement component 1, q subcomponent (C1qR1), C1qRp collectin receptor (C1qRp), or AA4 antigen.
- Distribution
- Expressed during immature B lymphocytes, hematopoietic progenitors and stem cells in bone marrow, immature dendritic cells, monocytes, macrophages, and endothelial cells.
- Function
- CD93 plays an important role in maintaining of plasma cells in bone marrow niches. It may play a role in uptake of particles by DC and the in vivo clearance of dying cells by macrophages.
- Cell Type
- B cells, Dendritic cells, Endothelial cells, Hematopoietic stem and progenitors, Macrophages, Monocytes
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
- Molecular Family
- CD Molecules
- Antigen References
-
1. Steinberger P, et al. 2002. J. Leukoc. Biol. 71:133
2. Chevrier S, et al. 2009. Proc. Nat. Acad. Sci. U. S. A. 106:3895
3. Norsworthy PJ, et al. 2004. J. Immunol. 172:3406
4. Li YS, et al. 1996. Immunity 5:527
5. Szilvassy SJ, et al. 1993. Blood 81:2310
- Gene ID
- 17064 View all products for this Gene ID
- UniProt
- View information about CD93 on UniProt.org
