PE anti-mouse CD287 (TLR7) Antibody
- 产品名称：
- PE anti-mouse CD287 (TLR7) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 160003
- 产品应用：
- 160003
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Ba/F3 cells expressing flag-6xHis-conjugated mouse TLR7
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
ICFC -?Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5??g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Kanno A, et al. 2013. Int Immunol. 25:413?
- RRID
- AB_2860749 (BioLegend Cat. No. 160003) AB_2876562 (BioLegend Cat. No. 160004)
- Structure
- Type 1 transmembrane protein, member of the Toll-like receptor (TLR) family
- Distribution
-
Myeloid and plasmacytoid dendritic cells, and B lymphocytes
- Function
- Pattern recognition receptor that detects single-stranded RNA, induces proinflammatory cytokine production
- Ligand/Receptor
- Single-stranded RNA
- Cell Type
- B cells, Dendritic cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, Innate Immune Signaling
- Antigen References
-
- Majer O, et al. 2019. Nature. 575:371.?
- Akilesh HM, et al. 2019. Science 363(6423)?
- Hemmi H, et al. 2002. Nat. Immunol. 3:196.?
- Gene ID
- 170743 View all products for this Gene ID
- UniProt
- View information about CD287 on UniProt.org
